No. |
Year |
Title |
Author |
Corresponding |
Journal |
Vol. |
Pages |
1 |
2013 |
Posttranscriptional Regulation of Histone Lysine Methyltransferase GLP in Embryonic Male Mouse Germ Cells. |
Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y |
Shinkai Y |
Biol Reprod. |
88 |
36 |
2 |
2013 |
Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes. |
Takahashi M, Kamei Y, Ehara T, Yuan X, Suganami T, Takai-Igarashi T, Hatada I, Ogawa Y |
Ogawa Y |
Biochem Biophys Res Commun. |
434 |
873-878 |
3 |
2013 |
miR-29 represses the activities of DNA methyltransferases and DNA demethylases. |
Morita S, Horii T, Kimura M, Ochiya T, Tajima S, Hatada I |
Hatada, I |
Int J Mol Sci |
14 |
14647-14658 |
4 |
2013 |
MiR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells. |
Gailhouste L, Gomez-Santos L, Hagiwara K, Hatada I, Kitagawa N, Kawaharada K, Thirion M, Kosaka N, Takahashi RU, Shibata T, Miyajima A, Ochiya T |
Ochiya T |
Hepatology |
58 |
1153-1165 |
5 |
2013 |
Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System. |
Horii T, Tamura D, Morita S, Kimura M, , Hatada I |
Hatada, I |
Int J Mol Sci |
14 |
19774-19781 |
6 |
2013 |
MiR-184 regulates insulin secretion through repression of Slc25a22. |
Morita S, Horii T, Kimura M, , Hatada I |
Hatada, I |
PeerJ |
1 |
e162 |
7 |
2013 |
Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system. |
Horii T, Morita S, Kimura M, Kobayashi R, Tamura D, Takahashi R, Kimura H, Suetake I, Ohata H, Okamoto K, Tajima S, Ochiya T, Abe Y, Hatada I |
Hatada, I |
PeerJ |
1 |
e230 |
8 |
2014 |
Paternal Allele Influences High Fat Diet-Induced Obesity. |
Morita S, Horii T, Kimura M, Arai Y, Kamai Y, Ogawa Y, Hatada I |
Hatada, I |
PLoS ONE |
9 |
e85477 |
9 |
2014 |
Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering. |
Horii T, Arai Y, Yamazai M, Morita S, Kimura M, Itoh M, Abe Y, Hatada I |
Hatada, I |
Scientific Reports |
4 |
4513 |
10 |
2015 |
Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the FattyAcid β-Oxidation Genes in the Postnatal Liver. |
Ehara T, Kamei Y, Yuan X, Takahashi M, Kanai S, Tamura E, Tsujimoto K, Tamiya T, Nakagawa Y, Shimano H, Takai-Igarashi T, Hatada I, Suganami T, Hashimoto K, Ogawa Y. |
Ogawa Y |
Diabetes |
64 |
775-784 |
11 |
2015 |
p53 Suppresses Tetraploid Development in Mice. |
Horii T, Yamamoto M, Morita S, Kimura M, Nagao Y, Hatada I |
Hatada, I |
Scientific Reports |
5 |
8907 |
13 |
2015 |
Genome Editing Using Mammalian Haploid Cells. |
Horii T, Hatada I |
Hatada I |
Int J Mol Sci |
16 |
23604-23614 |
14 |
2015 |
Global DNA hypomethylation and hypoxia-induced expression of the ten eleven translocation (TET) family, TET1, in scleroderma fibroblasts. |
Hattori M, Yokoyama Y, Hattori T1, Motegi S, Amano H, Hatada I, Ishikawa O. |
Amano H |
Exp Dermatol. |
24 |
841-846 |
15 |
2016 |
Genome editing: A breakthrough in life science and medicine. |
Hatada I, Horii T |
Hatada I |
Endocr J |
63 |
105-110 |
16 |
2016 |
Challenges to increasing targeting efficiency in genome engineering. |
Horii T, Hatada I |
Horii T |
J Reprod Dev |
62 |
7-9 |
17 |
2016 |
5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability. |
Kafer GR, Li X, Horii T, Suetake I, Tajima S, Hatada I, Carlton PM |
Carlton PM |
Cell Rep |
14 |
1283-1292 |
18 |
2016 |
Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity. |
Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I. |
Hatada I |
Sci Rep |
6 |
21693 |
19 |
2016 |
Structure and Engineering of Francisella novicida Cas9. |
Hirano H, Gootenberg JS, Horii T3, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F,Nishimasu H, Nureki O |
Nureki O |
Cell |
164 |
950-961 |
20 |
2016 |
Production of genome-edited pluripotent stem cells and mice by CRISPR/Cas. |
Horii T, Hatada I |
Hatada I |
Endocr J |
63 |
213-219 |
21 |
2016 |
The HUS1B promoter is hypomethylated in the placentas of low-birth-weight infants. |
Rumbajan JM, Yamaguchi Y, Nakabayashi K, Higashimoto K, Yastuki H, Nishioka K, Matsuoka K, Aoki S, Toda S, Takeda S, Seki H, Hatada I, Hata K, Soejima H, Joh K. |
Soejima H, Joh K |
Gene |
583 |
141-146 |
22 |
2016 |
Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells. |
Horii T, Hatada I. |
Horii T |
J Reprod Dev. |
62 |
331-335 |
23 |
2016 |
Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions. |
Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I. |
Hatada I |
Nat Biotech. |
34 |
1060-1065 |
24 |
2016 |
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. |
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F. |
Tokunaga F |
Nat Commun. |
7 |
12547 |
25 |
2017 |
TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes. |
Hasei J, Teramura T, Takehara T, Onodera Y, Horii T, Olmer M, Hatada I, Fukuda K, Ozaki T, Lotz MK, Asahara H. |
Asahara H |
Sci Rep |
7 |
42990 |
26 |
2017 |
Efficient generation of conditional knockout mice via sequential introduction of lox sites. |
Horii T, Morita S, Kimura M, Terawaki N, Shibutani M, Hatada I. |
Hatada I. |
Sci Rep |
7 |
7891 |
27 |
2017 |
Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions. |
Morita S, Horii T, Hatada I. |
Hatada I. |
Methods Mol Biol. |
1767 |
419-428 |
28 |
2018 |
Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood. |
Yuan X, Tsujimoto K, Hashimoto K, Kawahori K, Hanzawa N, Hamaguchi M, Seki T, Nawa M, Ehara T, Kitamura Y, Hatada I, Konishi M, Itoh N, Nakagawa Y, Shimano H, Takai-Igarashi T, Kamei Y, Ogawa Y. |
Ogawa Y |
Nat Commun. |
9 |
636 |
29 |
2019 |
Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. |
Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. |
Nureki O |
Nat Commun. |
10 |
1968 |
30 |
2020 |
DNA methylation analysis of multiple imprinted DMRs in Sotos syndrome reveals IGF2-DMR0 as a DNA methylation-dependent, P0 promoter-specific enhancer. |
Watanabe H, Higashimoto K, Miyake N, Morita S, Horii T, Kimura M, Suzuki T, Maeda T, Hidaka H, Aoki S, Yatsuki H, Okamoto N, Uemura T, Hatada I, Matsumoto N, Soejima H. |
Soejima H |
FASEB J. |
34 |
960-973 |
31 |
2020 |
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. |
Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, Georgel P, Hatada I, Chang B, Kerur N, Ambati BK, Ambati J, Gelfand BD. |
Gelfand BD |
Proc Natl Acad Sci U S A. |
117 |
2579-2587 |
32 |
2020 |
Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform. |
Morita S, Horii T, Kimura M, Hatada I. |
Hatada I |
Int J Mol Sci. |
21 |
E1574 |
33 |
2020 |
Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing. |
Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y. |
Hashimoto K, Ogawa Y. |
Sci Rep |
10 |
5181 |
34 |
2020 |
Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome. |
Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M & Hatada I. |
Hatada I. |
Genome Biology |
21 |
77 |
35 |
2020 |
Calcium-Free and Cytochalasin B Treatment Inhibits Blastomere Fusion in 2-Cell Stage Embryos for the Generation of Floxed Mice via Sequential Electroporation. |
Horii T, Kobayashi R, Kimura M, Morita S, Hatada I |
Hatada I. |
Cells |
9 |
pii: E1088 |
36 |
2020 |
Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity. |
Kohro Y, Matsuda T, Yoshihara K, Kohno K, Koga K, Katsuragi R, Oka T, Tashima R, Muneta S, Yamane T, Okada S, Momokino K, Furusho A, Hamase K, Oti T, Sakamoto H, Hayashida K, Kobayashi R, Horii T, Hatada I, Tozaki-Saitoh H, Mikoshiba K, Taylor V, Inoue K, Tsuda M |
Tsuda M |
Nat Neurosci. |
23 |
1376-1387 |
37 |
2021 |
The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice. |
Sugimoto H, Horii T, Hirota J, Sano Y, Shinoda Y, Konno A, Hirai H, Ishizaki Y, Hirase H, Hatada I, Furuichi T & Sadakata T. |
Sadakata T. |
Molecular Brain |
14 |
52 |
38 |
2021 |
α1A-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice. |
Shiraishi Y, Koga K, Yamagata R, Hatada I, Shiratori-Hayashi M, Tsuda M |
Tsuda M |
Molecular Brain |
14 |
55 |
39 |
2021 |
Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling. |
Kawanabe R, Yoshihara K, Hatada I, Tsuda M |
Tsuda M |
Molecular Brain |
14 |
79 |
40 |
2021 |
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. |
Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K. |
Yoshida K. |
Commun Biol. |
4 |
1204 |
41 |
2022 |
Stress-induced antinociception to noxious heat requires α 1A-adrenaline receptors of spinal inhibitory neurons in mice |
Uchiyama S, Yoshihara K, Kawanabe R, Hatada I, Koga K, Tsuda M. |
Tsuda M |
Molecular Brain |
15 |
6 |
42 |
2022 |
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+-activated large-conductance K + channels and motor coordination |
Watanave M, Takahashi N, Hosoi N, Konno A, Yamamoto H, Yasui H, Kawachi M, Horii T, Matsuzaki Y, Hatada I, Hirai H. |
Hirai H |
Proc Natl Acad Sci U S A |
119 |
e2113336119 |