We have shown that cells expressing PP (PP cells) act as a new cell of origin for pancreatic cancer. In this study, we generated mice that activate an oncogene (SV40T) in cells expressing th

• 2024/06/11
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Recently, common risk variants in the UNC13D gene were found by genome-wide association studies of asthma and obesity. Munc13-4, encoded by the UNC13D gene is known to regulate cytotoxic gra

• 2024/03/18
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Mitochondria are important organelles that supply energy to cells and have their own mitochondrial DNA. Interestingly, mitochondrial DNA is inherited only from the mother (maternal inheritan

• 2024/02/17
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In many sexually reproducing organisms, oocytes are fundamentally fertilized with one sperm. However, the mechanism of the polyspermy block, in which the oocyte only fertilizes with one of m

• 2024/01/29
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Cells in our body are subject to various stresses and damages, many of which are repaired. When the damage is severe, cells die by programmed cell death (apoptosis). However, how cells in di

• 2023/09/04
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