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群馬大学 生体調節研究所

アクセス アクセス

04/01/2020~03/31/2021

  1. Harada N, Hanada K, Minami Y, Kitakaze T, Ogata Y, Tokumoto H, Sato T, Kato S, Inui H, Yamaji R. (2020/4/1) Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. Am J Physiol Endocrinol Metab, 318(4), E525-E537. [PubMed]
  2. Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M & Hatada I. (2020/4/1) Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome. Genome Biology, 21(1),77. [PubMed]
  3. Murakami S., Mochimaru Y, Musha S, Kojima R., Deai M, Mogi C., Sato K, Okajima F, Tomura H. (2020/4/1) Species-dependent enhancement of ovarian cancer G protein-coupled receptor 1 activation by ogerin. Zoological Science, 37(2),103-108. [PubMed]
  4. Castaneda JM, Miyata H, Archambeault DR, Satouh Y, Yu Z, Ikawa M, Matzuk MM. (2020/4/15) Mouse t-complex protein 11 is important for progressive motility in sperm. Biol Reprod, 102(4),852-862. [PubMed]
  5. Taguchi K, Kajita K, Kitada Y, Fuwa M, Asano M, Ikeda T, Kajita T, Ishizuka T, Kojima I, Morita H.(2020/4/)Role of small proliferative adipocytes: possible beige cell progenitors. J Endocrinology, 245(1), 65-78. [PubMed]
  6. Musha S, Yoshida S, Murakami S, Kojima R, Deai M, Saso N, Mogi C, Sato K, Okajima F, Tomura H. (2020/4/10) Involvement of GPR4 in increased growth hormone and prolactin expressions by 1 extracellular acidification in MtT/S cells. Journal of Reproduction and Development, 66(2), 175-180. [PubMed]
  7. Suzuki E, Ogawa N, Takeda TA, Nishito Y, Tanaka YK, Fujiwara T, Matsunaga M, Ueda S, Kubo N, Tsuji T, Fukunaka A, Yamazaki T, Taylor KM, Ogra Y, Kambe T. (2020/4/24) Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation. J Biol Chem, 295(17), 5669-5684. [PubMed]
  8. Horii T, Kobayashi R, Kimura M, Morita S, Hatada I. (2020/4/28) Calcium-Free and Cytochalasin B Treatment Inhibits Blastomere Fusion in 2-Cell Stage Embryos for the Generation of Floxed Mice via Sequential Electroporation. Cells, 9(5), 1088. [PubMed]
  9. Fujitani Y. (2021/5/) How do you make new β-cells in humans? An attempt to create human β-cells from α-cells of brain-dead donors. J Diabetes Investig, 11(3), 513-515. [PubMed]
  10. Kurashima K, Kashiwagi H, Shimomura I, Suzuki A, Takeshita F, Mazevet M, Harata M, Yamashita T, Yamamoto Y, Kohno T and Shiotani B. (2020/5/1) SMARCA4 deficiency-associated heterochromatin induces intrinsic DNA replication stress and susceptibility to ATR inhibition in lung adenocarcinoma. NAR Cancer, 2(2), zcaa005. [PubMed]
  11. Hosooka T, Hosokawa Y, Matsugi K, Shinohara M, Senga Y, Tamori Y, Aoki C, Matsui S, Sasaki T, Kitamura T, Kuroda M, Sakaue H, Nomura K, Yoshino K, Nabatame Y, Itoh Y, Yamaguchi K, Hayashi Y, Nakae J, Accili D, Yokomizo T, Seino S, Kasuga M, Ogawa W. (2020/5/26) The PDK1-Foxo1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotrien B4 axis. Proc Natl Acad Sci U S A. 117(21), 11674-11684. [PubMed]
  12. Kohno D, Furusawa K, Kitamura T. (2020/5/28) Anagliptin suppresses diet-induced obesity through enhancing leptin sensitivity and ameliorating hyperphagia in high-fat high-sucrose diet fed mice. Endocr J, 67(5), 523-529. [PubMed]
  13. Kawamura A, Katayama Y, Nishiyama M, Shoji H, Tokuoka K, Ueta Y, Miyata M, Isa T, Miyakawa T, Hayashi-Takagi A, Nakayama KI. (2020/5/28) Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice.
    Hum Mol Genet. 29(8), 1274-1291. [PubMed]
  14. Gotoh N, Minato Y, Saitoh T, Takahashi N, Kasamatsu T, Souma K, Oda T, Hoshino T, Sakura T, Ishizaki T, Shimizu H, Takizawa M, Yokohama A, Tsukamoto N, Handa H, Murakami H. (2020/6/) PARP1 V762A polymorphism affects the prognosis of myelodysplastic syndromes. Eur J Haematol, 104(6), 526-537. [PubMed]
  15. Yo-hei Yamamoto, Ayano Kasai, Hiroko Omori, Tomoe Takino, Munechika Sugihara, Tetsuo Umemoto, Maho Hamasaki, Tomohisa Hatta, Tohru Natsume, Richard I. Morimoto, Ritsuko Arai, Satoshi Waguri, Miyuki Sato, Ken Sato, Shoshana Bar-Nun, Tamotsu Yoshimori, Takeshi Noda, Kazuhiro Nagata. (2020/6/3) ERdj8 governs the size of autophagosomes during the formation process. Journal of Cell Biology, 219(8), e201903127. [PubMed]
  16. Sato K, Mogi C, Mighell A.J, Okajima F. (2020/6/11) A missense mutation of Leu74Pro of OGR1 found in familial amelogenesis imperfecta actually causes the loss of the pH-sensing mechanism. Biochem Biophys Res Commun, 526(4), 920-926. [PubMed]
  17. Okunishi K, Wang H, Suzukawa M, Ishizaki R, Kobayashi E, Kihara M, Abe T, Miyazaki J, Horie M, Saito A, Saito H, Nakae S, and Izumi T. (2020/7/1) Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses. J. Clin. Invest, 130(7), 3919-3935. [PubMed]
  18. 北村忠弘. (2020/7) グルカゴン分泌異常. 月間糖尿病. 12, 54-59
  19. Nakai S, Oyabu M, Hatazawa Y, Akashi S, Kitamura T, Miura S, Kamei Y. (2020/7/1) FOXO1 suppresses PGC-1β gene expression in skeletal muscles. FEBS Open Bio, 10(7), 1373-1388. [PubMed]
  20. Shiono A, Sasaki H, Sekine R, Abe Y, Matsumura Y, Inagaki T, Tanaka T, Kodama T, Aburatani H, Sakai J, Takagi H. (2020/7/2) PPARα activation directly upregulates thrombomodulin in the diabetic retina. Sci. Rep, 10(1), 10837. [PubMed]
  21. Kobayashi M, Waki H, Nakayama H, Miyachi A, Mieno E, Hamajima H, Goto M, Yamada K, Yamauchi T, Kadowaki T, Kitamura T. (2020/7/16) Pseudo-hyperglucagonemia was observed in the pancreatectomized cases when measured by glucagon sandwich ELISA. J Diabetes Investig, 12(2), 286-289. [PubMed]
  22. Oginuma M, Harima Y, Tarazona OA, Diaz-Cuadros M, Michaut A, Ishitani T, Xiong F, Pourquié O. (2020/7/24)  Intracellular pH controls WNT downstream of glycolysis in amniote embryos. Nature, 584(7819), 98-101. [PubMed]
  23. Suga T, Sato K, Ohyama T, Matsui S, Kobayashi T, Tojima H, Horiguchi N, Yamazaki Y, Kakizaki S, Nishikido A, Okamura T, Yamada M, Kitamura T, Uraoka T. (2020/7/27) Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling. World J of Hepatol, 12(7), 350-362. [PubMed]
  24. Uzawa H, Kohno D, Koga T, Sasaki T, Fukunaka A, Okuno T, Watanabe A.J, Kazuno S, Miyatsuka T, Kitamira T, Fujitani Y, Watada H, Saeki K * and Yokomizo T. (2020/8/26) Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis. FASEB J, 34(10),13949-13958. [PubMed]
  25. Yamashita T. (2020/8/27) HSF1 Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway. Heat Shock Proteins, 1-12. [PubMed]
  26. Tsukiyama T, Zou J, Kim J, Ogamino S, Shino Y, Masuda T, Merenda A, Matsumoto M, Fujioka Y, Hirose T, Terai S, Takahashi H, Ishitani T, Nakayama KI, Ohba Y, Koo BK, Hatakeyama S. (2020/9/15) A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis. Nat Commun, 11(1), 4586. [PubMed]
  27. Handa H, Honma K, Oda T, Kobayashi N, Kuroda Y, Kimura-Masuda K, Watanabe S, Ishihara R, Murakami Y, Masuda Y, Tahara K, Takei H, Kasamatsu T, Saitoh T, Murakami H. (2020/9/27) Long Noncoding RNA PVT1 Is Regulated by Bromodomain Protein BRD4 in Multiple Myeloma and Is Associated with Disease Progression. Int. J. Mol. Sci, 21(19), 7121. [PubMed]
  28. Kobayashi M, Satoh H, Matsuo T, Kusunoki Y, Tokushima M, Watada H, Namba M, Kitamura T. (2020/9/28) Plasma glucagon levels measured by sandwich ELISA are correlated with impaired glucose tolerance in type 2 diabetes. Endocr J, 67(9), 903-922. [PubMed]
  29. Kyohara M, Shirakawa J, Okuyama T, Togashi Y, Inoue R, Li J, Miyashita D, Terauchi Y. (2020/9/29) Soluble EGFR, a hepatokine, and adipsin, an adipokine, are biomarkers correlated with distinct aspects of insulin resistance in type 2 diabetes subjects. Diabetol Metab Syndr, 12, 83. [PubMed]
  30. Wang H, Mizuno K, Takahashi N, Kobayashi E, Kasai H, Shirakawa J, Terauchi Y, Okunishi K, and Izumi T. (2020/9/29) Melanophilin accelerates granule fusion without predocking to the plasma membrane. Diabetes, 69(12), 2655-2666. [PubMed]
  31. 奥西勝秀, 泉哲郎. (2020/10/1) 糖尿病・内分泌代謝科. 51, 298-303.
  32. Kohro Y, Matsuda T, Yoshihara K, Kohno K, Koga K, Katsuragi R, Oka T, Tashima R, Muneta S, Yamane T, Okada S, Momokino K, Furusho A, Hamase K, Oti T, Sakamoto H, Hayashida K, Kobayashi R, Horii T, Hatada I, Tozaki-Saitoh H, Mikoshiba K, Taylor V, Inoue K, Tsuda M. (2020/10/5) Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity. Nat Neuroscience, 23(11), 1376-1387. [PubMed]
  33. Sato K, Tobo A., Mogi C, Tobo M, Yamane N, Tosaka M, Tomura H, Im D.-S, Okajima F. (2020/10/14) The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model. Scientific Reports, 10(11), 17193. [PubMed]
  34. Uehara T, Abe K, Oginuma M, Ishitani S, Yoshihashi H, Okamoto N, Takenouchi T, Kosaki K, Ishitani T. (2020/10/16) Pathogenesis of CDK8-associated disorder: two patients with novel CDK8 variants and in vitro and in vivo functional analyses of the variants. Sci Rep,10(1), 17575. [PubMed]
  35. Okuyama T, Shirakawa J, Tajima K, Ino Y, Vethe H, Togashi Y, Kyohara M, Inoue R, Miyashita D, Li J, Goto N, Ichikawa T, Yamasaki S, Ohnuma H, Takayanagi R, Kimura Y, Hirano H, Terauchi Y. (2020/10/21) Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor. Int J Mol Sci, 21(21), 7815. [PubMed]
  36. Konno K, Kulkeaw K, Sasada M, Nii T, Kaneyuki A, Ishitani T, Arai F, Sugiyama D. (2020/10/26) A novel method to purify neutrophils enables functional analysis of zebrafish hematopoiesis. Genes Cells, 25(12), 770-781. [PubMed]
  37. Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S. (2020/10/27)  GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons. FASEB J, 34,16601-16621. [PubMed]
  38. Sato Y, Rahman M.M, Haneda M, Tsuyama T, Mizumoto T, Yoshizawa T, Kitamura T, Gonzalez F.J, Yamamura K, Yamagata K. (2020/11/1) HNF1a controls glucagon secretion in pancreatic alpha cells through modulation of SGLT1. Biochim Biophys Acta Mol Basis Dis, 1866(11), 165898. [PubMed]
  39. Nagai S, Yoshida M, Takigawa Y, Torii S, Koshiishi I. (2020/11/1) Botanical sulfane sulfur donors inhibit ferroptotic cell death caused by the depletion of cysteine. Food Chem, 343, 128511. [PubMed]
  40. Morita R, Numata O, Nakano K, Takaine M. (2020/11/3) Cell cycle-dependent phosphorylation of IQGAP is involved in assembly and stability of the contractile ring in fission yeast. Biochemical and Biophysical Research Communications, 534, 1026-1032. [PubMed]
  41. Tatsuoka H, Sakamoto S, Yabe D, Kabai R, Kato U, Okumura T, Botagarova A, Tokumoto S, Usui R, Ogura M, Nagashima K, Mukai E, Fujitani Y, Watanabe A, Inagaki N. (2020/11/6) Single-Cell Transcriptome Analysis Dissects the Replicating Process of Pancreatic Beta Cells in Partial Pancreatectomy Model. iScience, 23(12), 101774. [PubMed]
  42. Harada N, Minami Y, Hanada K, Hanaoka R, Kobayashi Y, Izawa T, Sato T, Kato S, Inui H, Yamaji R. (2020/11/9) Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders. Gut Microbes, 12(1), 1817719. [PubMed]
  43. Gupta MK, Vethe H, Softic S, Rao TN, Wagh V, Shirakawa J, Barsnes H, Vaudel M, Takatani T, Kahraman S, Sakaguchi M, Martinez R, Hu J, Bjørlykke Y, Raeder H, Kulkarni RN. (2020/11/10) Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells. Stem Cell Reports, 15(5),1067-1079. [PubMed]
  44. Ninagawa S, Tada S, Okumura M, Inoguchi K, Kinoshita M, Kanemura S, Imami K, Umezawa H, Ishikawa T, Mackin RB, Torii S, Ishihama Y, Inaba K, Anazawa T, Nagamine T, Mori K. (2020/11/17) Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes. Elife, e60970. [PubMed]
  45. Sugiyama M, Yasunaga A, Kobayashi R, Fukasawa H, Hashimoto O, Kurusu S, Sasada H, Yoshioka K. (2020/11/26) Improvement in identification of pro-estrous mice by using a novel method of detecting vaginal mucous cells. Cell Tissue Res, 383(3),  1183-1190. [PubMed]
  46. Aoyama S, Nishida Y, Fujitani Y, Fukunaka A, Miyatsuka T, Suzuki L, Himuro M, Yoshimori T, Watada H. (2020/11/28) Rubicon in pancreatic beta cells plays a limited role in maintaining glucose homeostasis following increased insulin resistance. Endocr J, 67(11), 1119-1126. [PubMed]
  47. Charoensuka C, Jungtrakoon P, Chanprasert C, Tangjittipokin W, Shirakawa J, Togashi Y, Orime K, Songprakhon C, Chaichanad C, Abubakar Z, Ouying P, Sujjitjoon J, Doria A, Plengvidhya N, Yenchitsomanus P. (2020/12/11) Autosomal dominant diabetes associated with a novel ZYG11A mutation resulting in cell cycle arrest in beta-cells. Mol Cell Endocrinol, 522, 111126. [PubMed]
  48. Masataka Kunii, Yuria Noguchi, Shin-ichiro Yoshimura, Satoshi Kanda, Tomohiko Iwano, Erda Avriyanti, Nur Atik, Takashi Sato, Ken Sato, Masaharu Ogawa, and Akihiro Harada. (2021/1/4) SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity. Journal of Cell Biol, 220(1), e201910080. [PubMed]
  49. Mashun Onishi, Koji Yamano, Miyuki Sato, Noriyuki Matsuda, Koji Okamoto. (2021/2/1) Molecular mechanisms and physiological functions of mitophagy. EMBO J, 40(3), e104705. [PubMed]
  50. Kuramoto N, Nomura K, Kohno D, Kitamura T, Karsenty G, Hosooka T, Ogawa W. (2021/2/10) Role of PDK1 in skeletal muscle hypertrophy induced by mechanical load. Scientific Reports, 11(1), 3447. [PubMed]
  51. Okuyama T, Shirakawa J, Nakamura T, Murase T, Miyashita D, Inoue R, Kyohara M, Togashi Y, Terauchi Y. (2021/2/12) Association of the plasma xanthine oxidoreductase activity with the metabolic parameters and vascular complications in patients with type 2 diabetes. Sci Rep, 11(1), 3768. [PubMed]
  52. Taeko Sasaki, Miyuki Sato. (2021/2/24) Degradation of paternal mitochondria via mitophagy. Biochim Biophys Acta Gen Subj, 1865(6), 129886. [PubMed]
  53. Yoshizawa Y, Hosojima M, Kabasawa H, Tanabe N, Ugamura D, Koda Y, Shimada H, Takasawa T, Ito T, Kitamura T, Kobayashi M, Suzuki Y, Narita I, Saito A. (2021/3)  Effects of the once-weekly DPP4 inhibitor Omarigliptin on glycemic control in patients with type 2 siabetes mellitus on maintenance hemodialysis: a 24-week open-label, multicenter randomized controlled study. Diabetes Therapy, 12(3), 655-667. [PubMed]
  54. Sugimoto H, Horii T, Hirota J, Sano Y, Shinoda Y, Konno A, Hirai H, Ishizaki Y, Hirase H, Hatada I, Furuichi T & Sadakata T. (2021/3/12) The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice. Molecular Brain, 14(1), 52. [PubMed]
  55. Shiraishi Y, Koga K, Yamagata R, Hatada I, Shiratori-Hayashi M, Tsuda M. (2021/3/16) α1A-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice. Molecular Brain, 14(1) ,55. [PubMed]
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