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群馬大学 生体調節研究所

アクセス

Cell Signaling

Assistant Professor:Masakatsu Takaine
masaktakaine*gunma-u.ac.jp
(*=@)
Lab website
https://www.giar.gunma-u.ac.jp/program/program_takaine/

 

Member

Assistant Professor: Masakatsu Takaine
Post Doctoral Fellow: Kyohei Umebayashi

Research

Our lab aims to understand molecular mechanism by which cells respond to extracellular and intracellular signals. We take multifaceted approach combining Biochemistry, Genetics and Imaging to reveal mechanisms of action of key signaling molecules such as small GTPases, protein kinases and phosphatases.

ポンチ絵細胞シグナル(英)

 

On-going projects

  1. ATP homeostasis and cellular ageing
  2. A mechanism by which stresses activates Rho1-Pkc1 pathway
  3. Molecular mechanisms by which PP2A phosphatase is regulated upon stresses

 

Keywords

Yeast, Metabolism, Signal transduction, RhoGTPases, PP2A phosphatase, Inostol pyrophosphates. energy metabolism, ATP

Select References

  1. Takaine M. et al., (2019) J Cell Sci. inpress
  2. Ito H. et al., (2019) BBRC 511(4)
  3. Takaine M. et al., (2015) J Cell Sci. 128(15)
  4. Takaine M. et al., (2014) J Cell Sci. 15;127(20)

 

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