- 2025.07.28
- Press
- Joint
- 論文発表
- Imeglimin suppresses glucagon secretion and induces a loss of α-cell identity
- Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2025.07.14
- Press
- Joint
- 論文発表
- Adenylosuccinate mediates imeglimin-induced proliferative and antiapoptotic effects in β-cells.
- Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2025.03.14
- Press
- Joint
- 論文発表
- The antitumor effects of metformin are potentially mediated through LPA receptor inhibition
- Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2025.01.24
- Press
- Joint
- 論文発表
- The matricellular protein Fibulin-5 regulates β-cell proliferation in an autocrine/paracrine manner.
- Tomoko Okuyama, Takahiro Tsuno, Ryota Inoue, Setsuko Fukushima, Mayu Kyohara, Anzu Matsumura, Daisuke Miyashita, Kuniyuki Nishiyama, Yusuke Takano, Yu Togashi, Makiko Meguro-Horike, Shin-ichi Horike, Tatsuya Kin, A.M. James Shapiro, Hiromi Yanagisawa, Yasuo Terauchi, and Jun Shirakawa (Laboratory of Diabetes and Metabolic Disorders, Institute for Molecular and Cellular Regulation (IMCR), Gunma University, Japan; Department of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama City University, Yokohama, Japan; Research Center for Experimental Modeling of Human Disease, Kanazawa University, Kanazawa, Japan; Clinical Islet Laboratory and Clinical Islet Transplant Program, University of Alberta, Edmonton, AB T6G 2C8, Canada; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan;)(代謝疾患医科学分野)
- 2023.06.15
- Joint
- 論文発表
- Protective effects of the early combination therapy on β-cells
- Kuniyuki Nishiyama, Masato Ono, Takahiro Tsuno, Ryota Inoue, Ayako Fukunaka, Tomoko Okuyama, Mayu Kyohara, Yu Togashi, Setsuko Fukushima, Takuto Atsumi, Aoi Sato, Asuka Tsurumoto, Chisato Sakai, Yoshio Fujitani, Yasuo Terauchi, Shuichi Ito, and Jun Shirakawa (Lab. of Diabetes and Metabolic Disorders, Lab. of Developmental Biology and Metabolism, Yokohama City Univ.)(代謝疾患医科学分野)
- 2023.05.08
- Press
- Joint
- 論文発表
- A disproportionality analysis of the adverse effect profiles of methimazole and propylthiouracil in patients with hyperthyroidism using the Japanese Adverse Drug Event Report Database
- Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2022.11.24
- Press
- Joint
- 論文発表
- Protective effects of S100A8 on sepsis mortality: links to sepsis risk in obesity and diabetes.
- Miyashita D, Shirakawa J*, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2022.10.05
- Press
- Joint
- 論文発表
- E2F1 transcription factor mediates a link between fat and islets to promote β-cell proliferation in response to acute insulin resistance. Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)
- Jun Shirakawa(代謝疾患医科学分野)
- 2022.07.12
- Press
- Joint
- 論文発表
- Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER” Inoue R, Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)
- Inoue R, Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)
- 2021.10.01
- Press
- Joint
- 論文発表
- Imeglimin ameliorates β-cell apoptosis by modulating the endoplasmic reticulum homeostasis pathway
- Li J, Shirakawa J, et al. (Lab of Diabetes and Metabolic Disorders)(代謝疾患医科学分野)