04/01/2024~03/31/2025
- Ito R., Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M, noue S.I, Uchida A, Nakano K, Choi H, Yang G., Zhao Y, Yamaguchi R, Jin H., Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne T.F, Yoneshiro T, Matsumura Y, Sakai J. (2024/4/1) Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease. iScience, 27(4):109398. [PubMed]
- Maruyama T, Matsui S, Kobayashi R, Horii T, Oguri Y, Tsuzuki S, Horie T, Ono K, Hatada I, Sasak T. (2024/4/10) Medium-chain triglyceride-specific appetite is regulated by the β-oxidation of medium-chain fatty acids in the liver. Am J Physiol Endocrinol Metab, 326(5):E735-E746. [PubMed]
- Shoji M, Ohashi T, Nagase S, Yuri H, Ichihashi K, Takagishi T, Nagata Y, Nomura Y, Fukunaka A, Kenjou S, Miyake H, Hara T, Yoshigai E, Fujitani Y, Sakurai H, Dos Santos HG, Fukada T, Kuzuhara T. (2025/4/12) Possible involvement of zinc transporter ZIP13 in myogenic differentiation. Sci Rep, 14(1):8052. [PubMed]
- Fuwa, M., K. Kajita, I. Mori, M. Asano, T. Kajita, T. Senda, T. Inagaki and H. Morita. (2024/4/22) Mitochondrial fractions located in the cytoplasmic and peridroplet areas of white adipocytes have distinct roles. FEBS Lett, 598(14):1753-1768. [PubMed]
- Kurogi Y, Mizuno Y, Kamiyama T, Niwa R. (2024/4/26) The intestinal stem cell/enteroblast-GAL4 driver, escargot-GAL4, also manipulates gene expression in the juvenile hormone-synthesizing organ of Drosophila melanogaster. Sci Rep, 14(1):9631. [PubMed]
- Kitamura T and Kobayashi M. (2024/4/27) Advances in the clinical measurement of glucagon: from diagnosis to therapy. Diabetol Int, 15(3):362-369. [PubMed]
- Ogamino S, Yamamichi M, Sato K, Ishitani T. (2025/4/29) Dynamics of Wnt/β-catenin reporter activity throughout whole life in a naturally short-lived vertebrate. NPJ Aging, 10(1):23. [PubMed]
- Kazek M, Chodáková L, Lehr K, Strych L, Nedbalová P, McMullen E, Bajgar A, Opekar S, Šimek P, Moos M, Doležal T. (2024/5/7) Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila. PLoS Biol, 22(5):e3002299. [PubMed]
- Terui S, Igari M, Tsuno T, Okuyama T, Inoue R, Kyohara M, Terauchi Y, *Shirakawa J. (2024/5/15) Immediate impact of switching from dipeptidyl peptidase-4 (DPP-4) inhibitors to low-dose (0.3 mg) liraglutide on glucose profiles: A retrospective observational study. Diabetes Ther, 15(5):1139-1153. [PubMed]
- Singh A, Abhilasha KV, Acharya KR, Liu H, Nirala NK, Parthibane V, Kunduri G, Abimannan T, Tantalla J, Zhu LJ, Acharya JK, Acharya UR. (2024/5/23) A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila. Nat Commun, 5(1):4410. [PubMed]
- Singh A, Abhilasha KV, Acharya KR, Liu H, Nirala NK, Parthibane V, Kunduri G, Abimannan T, Tantalla J, Zhu LJ, Acharya JK, Acharya UR. (2024/5/23) A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila. Nat Commun, 15(1):4410. [PubMed]
- Pereye OB, Nakagawa Y, Sato T, Fukunaka A, Aoyama S, Nishida Y, Mizutani W, Kobayashi N, Morishita Y, Oyama T, Kawabata-Iwakawa R, Watada H, Mizukami H, Fukuda A, Fujitani Y. (2024/6/4) Identification of Ppy-lineage cells as a novel origin of pancreatic ductal adenocarcinoma. Journal of Pathology, 263(4-5):429-441. [PubMed]
- Abe K, Ino H, Niwa T, Semmy D, Takaochi A, Nishimura T, Mogi C, Uenaka M, Ishii M, Tanaka K, Ohkawa Y, Ishitani T. (2024/6/14) Sex-dependent regulation of vertebrate somatic growth and aging by germ cells. Sci Adv, 10(24):eadi1621. [PubMed]
- Kamimura I, Miyauchi E, Takeuchi T, Tsuchiya N, Tamura K, Uesugi A, Negishi H, Taida T, Kato T, Kawasumi M, Nagasawa M, Mogi K, Ohno H, Kikusui T. (2024/6/20) Modulation of gut microbiota composition due to early weaning stress induces depressive behavior during the juvenile period in mice. Anim Microbiome, 6(1):33. [PubMed]
- Kikuchi O, Ikeuchi Y, Kobayashi M, Tabei Y, Yokota-Hashimoto H, Kitamura T. (2024/6/21) Imeglimin enhances glucagon secretion via an indirect mechanism and improves fatty liver in HFHSD-fed mice. J Diabetes Investig, 15(9):1177-1190. [PubMed]
- Maejima I, Sato K. (2024/7/1) New aspects of a small GTPase RAB35 in brain development and function. Neural Regeneration Research, 20(7):1971-1980. [PubMed]
- Morita S, Horii T, Hatada I. (2024/7/17) Optimized Protocol for the Regulation of DNA Methylation and Gene Expression Using Modified dCas9-SunTag Platforms. Methods Mol. Biol, 2842:155-165. [PubMed]
- Satouh Y, Suzuki E, Sasaki K, Sato K. (2024/7/29) Improved low-invasive mRNA electroporation method into immature mouse oocytes visualizes protein dynamics during development. Biology of Reproduction, 111(4):931-941. [PubMed]
- Sakai M, Ohnishi K, Masuda M, Harumoto E, Fukuda T, Ohnishi A, Ishii S, Ohminami H, Yamanaka-Okumura H, Ohashi K, Itakura E, Horikawa K, Yonemura S, Hara T, Taketani Y. (2024/7) Modulations of the mTORC2-GATA3 axis by an isorhamnetin activated endosomal-lysosomal system of the J774.1 macrophage-like cell line. J Clin Biochem Nutr, 75(1):24-32. [PubMed]
- Kobayashi R, Tajika Y, Kohmaru J, Morita S, Horii T, Mizukami Y, Aikawa S, Hirota Y, Hatada I. (2024/8/8) The histone methyltransferase KMT2D is essential for embryo implantation via regulating precise differentiation of endometrial cells. Cell Death Discov, 10(1):357. 222:112094. [PubMed]
- Ohashi K, Otomo T. (2024/8) Structural Analyses of a GABARAP~ATG3 Conjugate Uncover a Novel Non-covalent Ubl-E2 Backside Interaction. bioRxiv [Preprint], 15:2024.08.14.607425. [PubMed]
- Honda M, Inoue R, Nishiyama K, Ueda T, Komuro A, Amano H, Sugisawa R, Dash S, Shirakawa J, Okada H. (2024/9/17) Vgll2 as an integrative regulator of mitochondrial function and contractility specific to skeletal muscle. J Cell Physiol, 239(12):e31436. [PubMed]
- Matsumoto R, Ogata K, Takahashi D, Kinashi Y, Yamada T, Morita R, Tanaka K, Hattori K, Endo M, Fujimura Y, Sasaki N, Ohno H, Ishihama Y, Kimura S, Hase K. (2024/10/5) AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine. Cell Mol Life Sci, ;81(1):425. [PubMed]
- Ishikawa K, Soejima S, Nishimura T, Saitoh S. (2024/10/8) Arrayed CRISPRi library to suppress genes required for Schizosaccharomyces pombe viability. J Cell Biol, 224(1):e202404085. [PubMed]
- Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Ogawa W. (2024/10/14) Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism. Mol Metab, 86:101968. [PubMed]
- Tahiri A, Youssef A, Inoue R, Moon S, Alsarkhi L, Berroug L, Nguyen XTA, Wang L, Kwon H, Pang ZP, Zhao JY, Shirakawa J, Ulloa L, El Ouaamari A. (2024/10/15) Vagal sensory neuron-derived FGF3 controls insulin secretion. Dev Cell, 60(1):51-61.e4. [PubMed]
- Gotoh N, Oda T, Kitamura Y, Shiraishi N, Aoyagi R, Omori A, Yanagisawa K, Iida M, Itai Y, Negishi H, Matsumura I, Kasamatsu T, Miyauchi E, Sasaki N, Takada S, Yokohama A, Handa H, Murakami H, Saitoh T. (2024/11/3) APEX1 Polymorphisms Affect Acute Myeloid Leukemia Risk, and Its Expression Is Involved in Cell Proliferation and Differentiation. Int J Lab Hematol, 47(2):276-287. [PubMed]
- Kurogi Y, Mizuno Y, Hayashi R, Goyins K, Okamoto N, Barton L, Niwa R. (2024/12/18) The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster. Open Biol, 14(12):240315. [PubMed]
- Yoshinari Y, Nishimura T, Yoshii T, Kondo S, Tanimoto H, Kobayashi T, Matsuyama M, Niwa R. (2024/12/30) A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster. Nat Commun, 15(1):10819. [PubMed]
- Ishima T, Kimura N, Kobayashi M, Watanabe C, Jimbo EF, Kobayashi R, Horii T, Hatada I, Murayama K, Ohtake A, Nagai R, Osaka H, Aizawa K. (2024/12/31) NADH Reductive Stress and Its Correlation with Disease Severity in Leigh Syndrome: A Pilot Study Using Patient Fibroblasts and a Mouse Model. Biomolecules, 15(1):38. [PubMed]
- Yamamoto Y, Sekine O, Ito-Kobayashi J, Nishida A, Togawa T, Ozamoto Y, Oe Y, Hagiwara A, Kobayashi M, Kitamura T, Iwanishi M, Shimatsu A, Kashiwagi A. (2025/1/15) Is glucose-induced hypersecretion of glicentin after the revision surgery using Roux-en-Y gastric bypass related to improved glycemic control due to insulin hypersecretion in a type 2 diabetes patient without diabetes remission after laparoscopic sleeve gastrectomy?. J Diabetes Investig, 16(2):343-347. [PubMed]
- Matsumura I, Oda T, Kasamatsu T, Murakami Y, Ishihara R, Ohmori A, Matsumoto A, Gotoh N, Kobayashi N, Miyazawa Y, Ogawa Y, Yokohama A, Sasaki N, Saitoh T, Handa H. (2025/1/29) Role of Rac1 in p53-Related Proliferation and Drug Sensitivity in Multiple Myeloma. Cancers, 17(3):461. [PubMed]
- Okuyama T, Tsuno T, Inoue R, Fukushima S, Kyohara M, Matsumura A, Miyashita D, Nishiyama K, Takano Y, Togashi Y, Meguro-Horike M, Horike S, Kin T, Shapiro AMJ, Yanagisawa H, Terauchi Y, *Shirakawa J. (2025/2/21) The matricellular protein Fibulin-5 regulates β-cell proliferation in an autocrine/paracrine manner. iScience, 28(2):111856. [PubMed]
- Hisaoka M, Komatsu T, Hashimoto T, Lin J, Ohkawa Y, Okuwaki M. (2025/3/2) Function of HP1BP3 as a linker histone is regulated by linker histone chaperones, NPM1 and TAF-I. Epigenetics Chromatin, 18(1):14. [PubMed]
- Oyabu M, Ohira Y, Fujita M, Yoshioka K, Kawaguchi R, Kubo A, Hatazawa Y, Yukitoshi H, Ortuste Quiroga HP, Horii N, Miura F, Araki H, Okano M, Hatada I, Gotoh H, Yoshizawa T, Fukada SI, Ogawa Y, Ito T, Ishihara K, Ono Y, Kamei Y. (2025/3/3) Dnmt3a overexpression disrupts skeletal muscle homeostasis, promotes an aging-like phenotype, and reduces metabolic elasticity. iScience, 28(4):112144. [PubMed]
- Nomura K, Yamasaki Y, Takeji K, Deha S, Yamashita K, Izumi-Mishima Y, Yasui-Yamada S, Kuroda M, Harada N, Kitamura T, Tsutsumi Y, Tsutsumi R, Nakaya Y, Sakaue H. (20253/8) Gut-pancreas axis in the control of insulin secretion in streptozotocin-resistant rats. Biochem Biophys Res Commun, 8:752:151487. [PubMed]
- Sato K, Ogasawara H, Ikeda Y, Kumagai H, Inoue R, Tsuno T, Matsunaga K, Ishida E, Shirakawa J. (2025/3/10) The antitumor effects of metformin are potentially mediated through LPA receptor inhibition. Diabetes Res Clin Pract, 222:112094. [PubMed]
- Yamada S, Ogawa H, Funato M, Kato M, Nakadate K, Mizukoshi T, Kawakami K, Kobayashi R, Horii T, Hatada I, Sakakibara SI. (2025/3/11) Induction of MASH-like pathogenesis in the Nwd1-/- mouse liver. Commun Biol, 8(1):348. [PubMed]
- Satouh Y, Tatebe T, Tanida I, Yamaguchi J, UchiyamaY, Sato K. (2025/3/17) Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition. eLife, 13:RP99358. [PubMed]
- Zou M, Tanabe K, Amo-Shiinoki K, Kohno D, Kagawa S, Shirasawa H, Ikeda K, Taguchi A, Ohta Y, Okuya S, Yamada T, Kitamura T, Masutani H, Tanizawa Y. (2025/3/21) Txnip deficiency causes a susceptibility to acute cold stress with brown fat dysfunction in mice. J Biol Chem, 301(3):108293. [PubMed]
- Kyohara M, Takayanagi R, Tsuno T, Ong Yajima E, Inoue R, Yamashita N, Okuyama T, Nishiyama K, Matsunaga K, Ishida E, Ito S, Terauchi Y, Goshima Y, Shirakawa J. (2025/3/27) Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets. Sci Rep, 15(1):10546. [PubMed]
- Ariyani W, Yoshikawa C, Tsuneoka H, Amano I, Imayoshi I, Ichinose H, Sumi-Ichinose C, Koibuchi N, Kitamura T, Kohno D. (2025/3/28) Dopaminergic neurons in the paraventricular hypothalamus extend the food consumption phase. Proc Natl Acad Sci U S A, 122(13):e2411069122. [PubMed]
- 佐々木 伸雄. (2024/7/1) オルガノイドを用いた粘膜エコシステムデザイン学. 腸内細菌学会誌, 38(4)229-232.
- 佐々木 伸雄, 今井 淳稀, 佐藤 俊朗. (2024/8/1) ヒト大腸オルガノイドを用いた腸内細菌との共培養研究. 腸内細菌学会誌, 38(3)157-166.
- 柳澤 宏太、今井 淳稀、佐々木 伸雄. (2024/8/1) 腸管オルガノイドを用いた宿主-腸内細菌の相互作用検証システムの開発. オルガノイド研究〜培養・作製,活用,臨床応用〜, 209-218.
- 佐藤 健. (2025/2/25) RING-CH型ユビキチンリガーゼMARC-3の解析からみえてきた早期多精拒否機構. 生化学, 97(1)91-94.
- 佐々木 伸雄. (2025/1/1) 腸内細菌叢は肥満や糖尿病と密接な関係がある. カラー図解 人体の細胞生物学, 258-259.
- 福中 彩子、藤谷 与士夫. (2025/2/1) 亜鉛トランスポーターZIPとZNTによる金属認識のメカニズム. 生体の科学, 101-106.
- 福中 彩子、藤谷 与士夫. (2025/2/1) 栄養学の温故知新 今こそ知りたい栄養管理の最前線 微量元素研究の最前線-微量金属元素の生体内・細胞内動態-. 診断と治療, 113.
- 藤谷 与士夫. (2025/2/28) 日本臨床 新時代の臨床糖尿病学(上)II. 血糖調節機構とその異常 膵島細胞の発生・分化機構. 日本臨床, 83.
- 北村 忠弘. グルカゴンから見た糖尿病診療. 内科.
- 北村 忠弘. グルカゴン・インクレチンの新たな側面とその応用. 実験医学, (42)2126-2140.
- 北村 忠弘. ELISA法による血漿中Glucagon測定キットGlucagon ELISA「コスミック」IIの基礎的検討. 医学と薬学.
- 北村 忠弘. グルカゴンーGLP-1―GIPの三角関係. 薬局, (76)95-100.
