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群馬大学 生体調節研究所

アクセス アクセス

04/01/2023~03/31/2024

  1. Izumi T. (2023/4/18) Multiple pathways and independent functional pools in insulin granule exocytosis. Genes Cells, 28;70(8):761-770. [PubMed]
  2. Izumi T. (2023/4/19) The GDF3-ALK7 signaling axis in adipose tissue: a possible therapeutic target for obesity and associated diabetes?. Endocr J, 70(8):761-770. [PubMed]
  3. Maejima I, Hara T, Tsukamoto S, Koizumi H, Kawauchi T, Akuzawa T, Hirai R, Kobayashi H, Isobe I, Emoto K, Kosako H, Sato K. (2023/4/21) RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution. Commun Biol, 6(1):440. [PubMed]
  4. Zhang JC, Yao W, Qu Y, Nakamura M, Dong C, Yang C, Ren Q, Ma M, Han M, Shirayama Y, Hayashi-Takagi A, Hashimoto K. (2023/5/17) Author Correction: Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype. Sci Rep, 13(1):8059. [PubMed]
  5. Okada M, Takano T, Ikegawa Y, Ciesielski H, Nishida H, Yoo SK. (2023/6/15) Oncogenic stress-induced Netrin is a humoral signaling molecule that reprograms systemic metabolism in Drosophila. EMBO J, 42(12):e111383. [PubMed]
  6. Takaine M, Morita R. (2023/6/26) Yeast PRPP amidotransferase assembles into fine granules to promote de novo purine synthesis through intermolecular substrate channeling. bioRxiv, 2023.06.05.543815
  7.  
  8. Suzuki T, Komatsu T, Shibata H, Tanioka A, Vargas D, Kawabata-Iwakawa R, Miura F, Masuda S, Hayashi M, Tanimura-Inagaki K, Morita S, Kohmaru J, Adachi K, Tobo M, Obinata H, Hirayama T, Kimura H, Sakai J, Nagasawa H, Itabashi H, Hatada I, Ito T, Inagaki T. (2023/7/7) Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity. Nucleic Acids Res, 51(12):6120-6142. [PubMed]
  9. Arai M, Tsuno T, Konishi H, Nishiyama K, Terauchi Y, Inoue R, Shirakawa J. (2023/7/13) A disproportionality analysis of the adverse effect profiles of methimazole and propylthiouracil in patients with hyperthyroidism using the Japanese Adverse Drug Event Report Database. Thyroid, 33(7):804-816. [PubMed]
  10. Nozawa K, Liao Z, Satouh Y, Geng T, Ikawa M, Monsivais D, Matzuk MM. (2023/8/1) Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in mice PLoS One, 18(8):e0289083. [PubMed]
  11. Fujimura T, Enomoto Y, Katsura H, Ogawa T, Baba S, Ogata A, Yamaoka A, Shiroguchi K, Morimoto M. Identifying a Lung Stem Cell Subpopulation by Combining Single-Cell Morphometrics, Organoid Culture, and Transcriptomics. (2023/8/16) Stem Cells, 41(8):809-820. [PubMed]
  12. Ito H, Yamada E, Kobayashi M, Horiguchi K, Okada S, Kitamura T, Yamada M. (2023/9/1) Total pancreatectomy in a patient treated with a sensor augmented pump showing no evidence of hyperglycemia or ketoacidosis without any insulin administration: A case report. Intern Med, 63(8):1125-1130. [PubMed]
  13. Chiang MH, Lin YC, Chen SF, Lee PS, Fu TF, Wu T, Wu CL. (2023/9/1) Independent insulin signaling modulators govern hot avoidance under different feeding states. PLoS Biol, 21(10):e3002332. [PubMed]
  14. Horiguchi K, Tsutsui Y, Fujiwara K, Tsukada T, Nakakura T, Yoshida S, Hasegawa R, Takigami S. (2023/9/30) Fluctuation of CD9/SOX2-positive cell populations during the turnover of GH- and TSH-producing cells in the adult anterior pituitary gland. J Reprod Dev, 69(6):308-316. [PubMed]
  15. Himuro M, Wakabayashi Y, Taguchi T, Katahira T, Suzuki L, Iida H, Ogihara T, Nishida Y, Sasaki S, Lynn FC, Hiraoka Y, Oshima S, Okamoto R, Fujitani Y, Watada H, Miyatsuka T. (2023/10/23) Novel time-resolved reporter mouse reveals spatial and transcriptional heterogeneity during alpha cell differentiation. Diabetologia, 67(1):156-169. [PubMed]
  16. Kasamatsu T, Awata-Shiraiwa M, Ishihara R, Murakami Y, Masuda Y, Gotoh N, Oda T, Yokohama A, Matsumura I, Handa H, Tsukamoto N, Murakami H, Saitoh T. (2023/10) Sub-lethal doses of chemotherapeutic agents induce senescence in T cells and upregulation of PD-1 expression. Clin Exp Med, 23(6):2695-2703. [PubMed]
  17. Temma Y, Obi-Nagata K, Hoshiba Y, Miyake R, Katayama Y, Hagihara H, Suzuki N, Miyakawa T, Nakayama KI, Hayashi-Takagi A. (2023/11/29) Effect of brain acidification on depression-related behaviors in diabetes mellitus. Front Psychiatry, 14:1277097. [PubMed]
  18. Sasaki T, Kushida Y, Norizuki T, Kosako H, Sato K, Sato M. (2024/2/17) ALLO-1- and IKKE-1-dependent positive feedback mechanism promotes the initiation of paternal mitochondrial autophagy. Nat Commun, 15(1):1460. [PubMed]
  19. Sulekh S, Ikegawa Y, Naito S, Oji A, Hiratani I, Yoo SK. (2024/1/31) A feedback loop that drives cell death and proliferation and its defect in intestinal stem cells. Life Sci Alliance, 7(4):e202302238. [PubMed]
  20. Nishida J, Tsuno T, G Yabe S, Kin T, Fukuda S, Takeda F, Shirakawa J, Okochi H. (2024/3/28) Encapsulated human islets in alginate fiber maintain long-term functionality. Endocr J, 71(3):253-264. [PubMed]
  21. Terui S, Igari M, Tsuno T, Okuyama T, Inoue R, Kyohara M, Terauchi Y, Shirakawa J. (2024/3/15) Immediate Impact of Switching from Dipeptidyl Peptidase 4 (DPP4) Inhibitors to Low-Dose (0.3mg) Liraglutide on Glucose Profiles: A Retrospective Observational Study. Diabetes Ther, (5):1139-1153. [PubMed]
  22. Chaomulige, Matsuo T, Sugimoto K, Miyaji M, Hosoya O, Ueda M, Kobayashi R, Horii T, Hatada I. (2024/2/5) Morphometric Analysis of the Eye by Magnetic Resonance Imaging in MGST2– Gene-Deficient Mice. Biomedicines, 12(2):370. [PubMed]
  23. Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Miyakawa T. (2024/3/26) Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. Elife, 12:RP89376. [PubMed]
  24. Okunishi k, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T. (2024/3/31) Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen-presenting cells. Allergy, 79(7):1992-1995. [PubMed]
  25. Nakamura Y, Horie I, Kitamura T, Kusunoki Y, Nishida K, Yamamoto A, Hirota Y, Fukui T, Maeda Y, Minami M,
    Matsui T, Kawakami A, Abiru N. (2024/1/22) Glucagon secretion and its association with glycaemic control and ketogenesis during sodium-glucose cotransporter 2 inhibition by ipragliflozin in people with type 1 diabetes: Results from the multicentre, open-label, prospective study. Diabetes Obes Metab, 26(5):1605-1614. [PubMed]
  26. Kitamura T. (2024/2/22) Glucagon: Physiological and Pharmacological Functions and Pathophysiological Significance in Type 2 Diabetes. Glucagon: Physiological and Pharmacological Functions and Pathophysiological Significance in Type 2 Diabetes. Endocrinol Metab (Seoul), 39(1):33-39. [PubMed]
  27. Kitamura T. (2024/3/19) Useful biomarkers and clinical characteristics of post-pancreatitis diabetes mellitus (PPDM). J Clin Endocrinol Metab, dgae174. [PubMed]
  28. Maejima I and Sato K. (2024/3/1) New aspects of a small GTPase RAB35 in brain development and function. Neural Regen Res, 20(7):1971-1980. [PubMed]
  29. Kawasaki I, Sugiura K, Sasaki T, Matsuda N, Sato M, Sato K. (2024/1/26) MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans. Nat Commun, 15(1):792. [PubMed]
  30. Ichikawa R, Takano K, Fujimoto K, Kobayashi M, Kitamura T, Shichiri M, Miyatsuka T. (2023/10) Robust increase in glucagon secretion after oral protein intake but not after glucose or lipid intake in Japanese non-diabetic subjects. J Diabetes Investig, 14(10):1172-1174. [PubMed]
  31. Umeda S, Sujino T, Miyamoto K, Yoshimatsu Y,  Harada Y, Nishiyama K,  Aoto Y,  Adachi K, Hayashi N, Amafuji K, Moritoki N, Shibata S, Sasaki N, Mita M, Tanemoto S, Ono K, Mikami Y, Sasabe J, Takabayashi K, Hosoe N, Suzuki T, Sato T, Atarashi K, Teratani T, Ogata H, Nakamoto N, Shiomi D, Ashida H, Kanai T. (2023/12/13) D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol
    ,16(6):1011-1031. [PubMed]
  32. Yamamoto Y, Togawa T, Sekine O, Ozamoto Y, Fuse J, Azuma C, Ito-Kobayashi J, Oe Y, Hagiwara A, Kobayashi M, Kitamura T, Iwanishi M, Shimatsu A, Kashiwagi A. (2023/12/28) The oral disposition index calculated from a meal tolerance test is a crucial indicator for evaluating differential normalization of postprandial glucose and triglyceride excursions in morbidly obese patients after laparoscopic sleeve gastrectomy. Endocr J, 70(12):1141-1157. [PubMed]
  33. Nishiyama K, Ono M, Tsuno T, Inoue R, Fukunaka A, Okuyama T, Kyohara M, Togashi Y, Fukushima S, Atsumi T, Sato A, Tsurumoto A, Sakai C, Fujitani Y, Terauchi Y, Ito S, Shirakawa J. (2023/8/1) Protective effects of imeglimin and metformin combination therapy on β-cells in db/db male mice. Endocrinology, 164(8):bqad095. [PubMed]
  34. Moon S, Alsarkhi L, Lin TT, Inoue R, Tahiri A, Colson C, Cai W, Shirakawa J, Qian WJ, Zhao JY, El Ouaamari A. (2023/9/11) Transcriptome and secretome profiling of sensory neurons reveals sex differences in pathways relevant to insulin sensing and insulin secretion. FASEB J, 37(10):e23185. [PubMed]
  35. Kurogi Y, Imura E, Mizuno Y, Hoshino R, Nouzova M, Matsuyama S, Mizoguchi A, Kondo S, Tanimoto H, Noriega FG, Niwa R. (2023/5/15) Female reproductive dormancy in Drosophila is regulated by DH31-producing neurons projecting into the corpus allatum. Development, 150(10):dev201186. [PubMed]
  36. Okada M, Takano T, Ikegawa Y, Ciesielski H, Nishida H, Yoo SK. (2023/6/15) Oncogenic stress-induced Netrin is a humoral signaling molecule that reprograms systemic metabolism in Drosophila. EMBO J, 42(12):e111383. [PubMed]
  37. Kobayashi R, Kawabata-Iwakawa R, Terakawa J, Sugiyama M, Morita S, Horii T, Hatada I. (2023/8) Aberrant activation of estrogen receptor-α signaling in Mettl14-deficient uteri impairs embryo implantation. FASEB J, 37(8):e23093. [PubMed]
  38. Yamada T, Yoshinari Y, Tobo M, Habara O, Nishimura T. (2023/9/1) Nacα protects the larval fat body from cell death by maintaining cellular proteostasis in Drosophila. Nat Commun, 14(1):5328. [PubMed]
  39. Morita S, Horii T, Kimura M, Kobayashi R, Tanaka H, Akita H, Hatada I. (2023/9/19) A Lipid Nanoparticle-Based Method for the Generation of Liver-Specific Knockout Mice. Int J Mol Sci, 24(18):14299. [PubMed]
  40. Schwartz U, Komatsu T, Huber C, Lagadec F, Baumgartl C, Silberhorn E, Nuetzel M, Rayne F, Basyuk E, Bertrand E, Rehli M, Wodrich H, Laengst G. (2023/10/4) Changes in adenoviral chromatin organization precede early gene activation upon infection. EMBO J, 42(19):e114162. [PubMed]
  41. Chiang MH, Lin YC, Chen SF, Lee PS, Fu TF, Wu T, Wu CL. (2023/10/17) Independent insulin signaling modulators govern hot avoidance under different feeding states. PLoS Biol, 21(10):e3002332. [PubMed]
  42. Yoshikawa C, Ariyani W, Kohno D. (2023/12/30) DNA Methylation in the Hypothalamic Feeding Center and Obesity. J Obes Metab Syndr, 32(4):303-311. [PubMed]
  43. Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Ogawa W. (2024/1/15) Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism. Mol Metab, 86:101968. [PubMed]
  44. Taniuchi Y, Hiraide K, Su R, Ijuin K, Wei X, Horii T, Hatada I, Lee J. (2023/2/3) Analysis of absolute amounts of two meiotic cohesin subunits, RAD21L and REC8, in mouse spermatocytes. J Reprod Dev, 69(2):78-86. [PubMed]
  45. Ito R, Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M., noue S.I, Uchida A., Nakano K, Choi H, Yang G, Zhao Y, Yamaguchi R, Jin H, Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne T.F, Yoneshiro T, Matsumura Y, Sakai J. (2024/3/1) Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease. iScience, 27(4):109398. [PubMed]
  46. 北村忠弘. (2023/10) グルカゴンの正確な測定系の開発と,その有用性. 肥満研究.
  47. 北村忠弘. (2023/8) . グルカゴンの生理的役割と糖尿病における意義は?. 内分泌代謝疾患Clinical Question 100.
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