Professor: FUJITANI Yohio
fujitani*gunma-u.ac.jp
(*=@)
Lab website
http://tou-taisha.imcr.gunma-u.ac.jp/
Member
Professor: FUJITANI Yoshio
Associate Professor: SATO Takashi
Assistant Professor: FUKUNAKA Ayako
Assistant Professor: NAKAGAWA Yuko
Technical Officer: KOHMARU Junki
Technical Assistant: SUDA Asuka
Technical Assistant: TAMURA Yasuko
Technical Assistant: MIZUTANI Wakana
Technical Assistant: ISHIZAKA Tomomi
Graduate Student: SHIMADA Masaharu
Graduate Student: Zhehao ZHANG
Graduate Student: ISOZAKI Azu
Undergraduate Student: OGAWA Mahiro
Undergraduate Student: KOBAYASHI Nanami
Undergraduate Student: MA Yingzhu
Research
The dysfunction of pancreatic b cells and brown adipocytes can cause diabetes and metabolic syndrome. Our goal is to elucidate the molecular mechanism involved in the maintenance of homeostasis of these higher-order function cells, which is the key to glucose metabolism. We aim to elucidate the mechanism of cellular homeostasis, from a variety of viewpoints, including developmental biology, zinc biology, and autophagy by effectively utilizing genetically engineered mice. Furthermore, using our findings from basic medical research, we aim to establish a groundbreaking treatment for diabetes and obesity.
On-going projects
- Research on the developmental biology of pancreatic b cells
- Analysis of zinc transporters involved in the browning of adipocytes
- Analysis of a new type of pancreatic cancer arising from islets
Keywords
diabetes, glucose metabolism, developmental biology, pancreatic b cells, genetically engineered mice, brown adipocytes, zinc biology, pancreatic cancer
Select References
- Pereye OB. et al (2024) J Pathol in press
- Fukunaka A. et al (2023) Sci Rep 15;13(1) :3484 doi: 10.1038/s41598-023-30498-y.
- Aoyama S. et al (2023) Cell Chem Biol 30(6):658-671.e4. doi: 10.1016/j.chembiol.2023.03.001.
- Saito D. et al (2022) PLoS One 17(8):e0269958. doi: 10.1371/journal.pone.0269958.
- Fukaishi T. et al. (2021) Diabetologia 64(12):2803-2816. doi: 10.1007/s00125-021-05560-x.
