{"id":14574,"date":"2025-03-14T09:23:44","date_gmt":"2025-03-14T00:23:44","guid":{"rendered":"https:\/\/www.imcr.gunma-u.ac.jp\/?p=14574"},"modified":"2025-03-14T09:23:44","modified_gmt":"2025-03-14T00:23:44","slug":"%e3%80%90%e3%83%97%e3%83%ac%e3%82%b9%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%80%91%e7%b3%96%e5%b0%bf%e7%97%85%e6%b2%bb%e7%99%82%e8%96%ac%e3%81%ae%e6%96%b0%e3%81%9f%e3%81%aa%e6%8a%97%e8%85%ab%e7%98%8d","status":"publish","type":"post","link":"https:\/\/www.imcr.gunma-u.ac.jp\/?p=14574","title":{"rendered":"\u3010\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u3011\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u306e\u65b0\u305f\u306a\u6297\u816b\u760d\u52b9\u679c\u3092\u767a\u898b"},"content":{"rendered":"<p>\u7fa4\u99ac\u5927\u5b66\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240\uff08\u7fa4\u99ac\u770c\u524d\u6a4b\u5e02\uff09\u306e\u3001\u767d\u5ddd\u7d14\u6559\u6388\u3001\u4f50\u85e4\u5e78\u5e02\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u682a\u5f0f\u4f1a\u793e\u30bf\u30f3\u30bd\u30fc\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\uff08\u6771\u4eac\uff09\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3067\u3042\u308b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u304c\u3001\u30ea\u30be\u30db\u30b9\u30d5\u30a1\u30c1\u30b8\u30f3\u9178\uff08LPA: Lysophosphatidic Acid\uff09\u53d7\u5bb9\u4f53\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u6297\u816b\u760d\u52b9\u679c\u3092\u793a\u3059\u53ef\u80fd\u6027\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<br \/>G\u30bf\u30f3\u30d1\u30af\u8cea\u5171\u5f79\u53d7\u5bb9\u4f53\uff08GPCR: G protein-coupled receptor\uff09\u306f\u3001\u764c\u6cbb\u7642\u306e\u6a19\u7684\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u6297\u816b\u760d\u52b9\u679c\u3092\u6301\u3064\u3053\u3068\u306f\u77e5\u3089\u308c\u3066\u3044\u308b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u306eGPCR 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\/>\u65e5\u672c\u4eba\u306e\u7cd6\u5c3f\u75c5\u3092\u6709\u3059\u308b\u4eba\u3067\u3082\u60aa\u6027\u816b\u760d\uff08\u764c\uff09\u306f\u6b7b\u56e0\u306e1\u4f4d\u3067\u3042\u308a\u3001\u7279\u306b\u809d\u7d30\u80de\u764c\u306a\u3069\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u306e\u65b0\u305f\u306a\u6a19\u7684\u3092\u4ecb\u3057\u305f\u6297\u816b\u760d\u52b9\u679c\u306e\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3001\u809d\u7d30\u80de\u764c\u306e\u6cbb\u7642\u6cd5\u958b\u767a\u306b\u8ca2\u732e\u3059\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n<p>\u30fb\u96d1\u8a8c\u540d\uff1aDiabetes Res Clin Pract\u8a8c\uff08\u56fd\u969b\u7cd6\u5c3f\u75c5\u9023\u5408: IDF\uff09<br \/>\u30fb\u516c\u958b\u65e5\uff1a2025\u5e743\u670810\u65e5<br \/>\u30fb\u30bf\u30a4\u30c8\u30eb\uff1aThe antitumor effects of metformin are potentially mediated through LPA receptor inhibition<\/p>\n<p>\u7814\u7a76\u5185\u5bb9\u306e\u8a73\u7d30\u306f<a href=\"https:\/\/www.imcr.gunma-u.ac.jp\/?post_type=research_result&amp;p=14580\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3092\u3054\u89a7\u306b\u306a\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u8cc7\u6599\u306f<a href=\"https:\/\/www.imcr.gunma-u.ac.jp\/cms_imcr\/wp-content\/uploads\/2025\/03\/20250314-Press-Diabetes-Res-Clin-Pract.pdf\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3092\u3054\u89a7\u306b\u306a\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7fa4\u99ac\u5927\u5b66\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240\uff08\u7fa4\u99ac\u770c\u524d\u6a4b\u5e02\uff09\u306e\u3001\u767d\u5ddd\u7d14\u6559\u6388\u3001\u4f50\u85e4\u5e78\u5e02\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u682a\u5f0f\u4f1a\u793e\u30bf\u30f3\u30bd\u30fc\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\uff08\u6771\u4eac\uff09\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3067\u3042\u308b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u304c\u3001\u30ea\u30be\u30db\u30b9\u30d5\u30a1\u30c1\u30b8\u30f3\u9178\uff08LPA: Lysop [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3,61,10],"tags":[],"class_list":["post-14574","post","type-post","status-publish","format-standard","hentry","category-information","category-research","category-important"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.2 - aioseo.com -->\n\t<meta name=\"description\" content=\"\u7fa4\u99ac\u5927\u5b66\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240\uff08\u7fa4\u99ac\u770c\u524d\u6a4b\u5e02\uff09\u306e\u3001\u767d\u5ddd\u7d14\u6559\u6388\u3001\u4f50\u85e4\u5e78\u5e02\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u682a\u5f0f\u4f1a\u793e\u30bf\u30f3\u30bd\u30fc\u30d0\u30a4\u30aa\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"sysad\"\/>\n\t<link 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