{"id":12277,"date":"2023-07-14T14:12:17","date_gmt":"2023-07-14T05:12:17","guid":{"rendered":"https:\/\/www.imcr.gunma-u.ac.jp\/?p=12277"},"modified":"2023-07-14T14:18:25","modified_gmt":"2023-07-14T05:18:25","slug":"rna%e3%81%ae%e3%83%a1%e3%83%81%e3%83%ab%e5%8c%96%e4%bf%ae%e9%a3%be%e5%88%b6%e5%be%a1%e3%81%af%e8%83%9a%e7%9d%80%e5%ba%8a%e3%81%ae%e6%88%90%e7%ab%8b%e3%81%ab%e4%b8%8d%e5%8f%af%e6%ac%a0%e3%81%a7","status":"publish","type":"post","link":"https:\/\/www.imcr.gunma-u.ac.jp\/?p=12277","title":{"rendered":"\u3010\u7814\u7a76\u6210\u679c\u767a\u8868\u3011RNA\u306e\u30e1\u30c1\u30eb\u5316\u4fee\u98fe\u5236\u5fa1\u306f\u80da\u7740\u5e8a\u306e\u6210\u7acb\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b"},"content":{"rendered":"<p>\u30b2\u30ce\u30e0\u79d1\u5b66\u30ea\u30bd\u30fc\u30b9\u5206\u91ce\u306e\u5c0f\u6797\u826f\u7950\u7814\u7a76\u54e1\u3001\u7551\u7530\u51fa\u7a42\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5b50\u5bae\u306b\u304a\u3051\u308bRNA\u30e1\u30c1\u30eb\u5316\u4fee\u98fe\u5236\u5fa1\u304c\u30de\u30a6\u30b9\u80da\u7740\u5e8a\u306e\u6210\u7acb\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<br \/>\u8fd1\u5e74\u3001RNA\u5206\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u4fee\u98fe\u306e\u4e00\u3064\u3067\u3042\u308bN6\u30e1\u30c1\u30eb\u30a2\u30c7\u30ce\u30b7\u30f3\uff08m6A\uff09\u304c\u69d8\u3005\u306a\u751f\u547d\u73fe\u8c61\u3084\u75be\u60a3\u75c5\u614b\u3092\u5236\u5fa1\u3059\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u6a5f\u69cb\u3068\u3057\u3066\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u6211\u3005\u306f\u3001RNA m6A\u4fee\u98fe\u306b\u91cd\u8981\u306aMettl14\u3068\u3044\u3046\u907a\u4f1d\u5b50\u3092\u5b50\u5bae\u7279\u7570\u7684\u306b\u6b20\u640d\u3055\u305b\u305f\u907a\u4f1d\u5b50\u6539\u5909\u30de\u30a6\u30b9\u3092\u4f5c\u51fa\u3057\u3001Mettl14\u6b20\u640d\u96cc\u30de\u30a6\u30b9\u306f\u5b50\u5bae\u306b\u304a\u3051\u308b\u30a8\u30b9\u30c8\u30ed\u30b8\u30a7\u30f3\u5fdc\u7b54\u6027\u30b7\u30b0\u30ca\u30eb\u306e\u7570\u5e38\u6d3b\u6027\u5316\u306b\u3088\u308a\u3001\u7740\u5e8a\u4e0d\u5168\u306b\u3088\u308b\u4e0d\u598a\u3068\u306a\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<br \/>\u672c\u7814\u7a76\u306e\u6210\u679c\u306b\u3088\u308a\u3001\u7fd2\u6163\u6027\u6d41\u7523\u3092\u306f\u3058\u3081\u3068\u3057\u305f\u598a\u5a20\u521d\u671f\u6d41\u7523\u306e\u8a3a\u65ad\u3084\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u5411\u3051\u305f\u7814\u7a76\u3078\u306e\u5c55\u958b\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u30fb\u96d1\u8a8c\u540d\uff1aThe FASEB Journal<br \/>\u30fb\u516c\u958b\u65e5\uff1a2023\u5e747\u670813\u65e5<br \/>\u30fb\u30bf\u30a4\u30c8\u30eb\uff1a\u201dAberrant activation of estrogen receptor-\u03b1 signaling in Mettl14-deficient uteri impairs embryo implantation\u201d<\/p>\n<p>\u7814\u7a76\u5185\u5bb9\u306e\u8a73\u7d30\u306f<a href=\"https:\/\/www.imcr.gunma-u.ac.jp\/?research_result=12279-2\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3092\u3054\u89a7\u306b\u306a\u3063\u3066\u304f\u3060\u3055\u3044<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b2\u30ce\u30e0\u79d1\u5b66\u30ea\u30bd\u30fc\u30b9\u5206\u91ce\u306e\u5c0f\u6797\u826f\u7950\u7814\u7a76\u54e1\u3001\u7551\u7530\u51fa\u7a42\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5b50\u5bae\u306b\u304a\u3051\u308bRNA\u30e1\u30c1\u30eb\u5316\u4fee\u98fe\u5236\u5fa1\u304c\u30de\u30a6\u30b9\u80da\u7740\u5e8a\u306e\u6210\u7acb\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u8fd1\u5e74\u3001RNA\u5206\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u4fee\u98fe\u306e\u4e00\u3064\u3067\u3042\u308bN6\u30e1\u30c1\u30eb\u30a2\u30c7\u30ce\u30b7\u30f3 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3,61],"tags":[],"class_list":["post-12277","post","type-post","status-publish","format-standard","hentry","category-information","category-research"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.2.1 - 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