{"id":12270,"date":"2023-10-06T14:19:08","date_gmt":"2023-10-06T05:19:08","guid":{"rendered":"https:\/\/www.imcr.gunma-u.ac.jp\/?page_id=12270"},"modified":"2023-10-19T11:05:26","modified_gmt":"2023-10-19T02:05:26","slug":"__trashed","status":"publish","type":"page","link":"https:\/\/www.imcr.gunma-u.ac.jp\/?page_id=12270","title":{"rendered":"\u4ee4\u548c3\u5e74\u5ea6(2021\u5e744\u67081\u65e5\uff5e2022\u5e743\u670831\u65e5\uff09"},"content":{"rendered":"
    \n
  1. Kawanabe R, Yoshihara K, Hatada I, Tsuda M. (2021\/5\/10) Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling. Molecular Brain, 14(1),79. [PubMed<\/span><\/a>]<\/li>\n
  2. Takaine M. (2021\/5\/28) Assessment of Cytotoxicity of alpha-Synuclein in Budding Yeast Using a Spot Growth Assay and Fluorescent Microscopy. Methods Mol Biol, 2322,163-174. [PubMed<\/a><\/span>]<\/li>\n
  3. WK Martins, MN da Silva, K Pandey, I Maejima, E Ramalho, VC Olivon, SN Diniz, D Grasso. (2021\/6\/1) Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions. Curr Res Pharmacol Drug Discov,\u00a0 j.crphar.2021.100033. [PubMed<\/a><\/span>]<\/li>\n
  4. JM Castaneda, K Shimada, Y Satouh, Z Yu, M Ikawa, MM Matzuk. (2021\/6\/10) FAM209 associates with DPY19L2 and is required for sperm acrosome biogenesis and fertility in mice. J Cell Sci, 134(21):jcs259206.
    [    PubMed<\/a><\/span>]<\/li>\n
  5. Hasebe M, Shirakawa J, Miyashita D, Kunishita R, Kyohara M, Okuyama T, Togashi Y, Terauchi Y. (2021\/6\/22) Asymptomatic meningitis diagnosed by positron emission tomography in a patient with syndrome of inappropriate antidiuretic hormone secretion: a case report, J Med Case Rep, 15(1):390. [PubMed<\/a><\/span>]<\/li>\n
  6. Inoue R, Nishiyama K, Li J, Miyashita D, Ono M, Terauchi Y, Shirakawa J. (2021\/6\/24) The Feasibility and Applicability of Stem Cell Therapy for the Cure of Type 1 Diabetes. Cells, 10(7):1589. [PubMed]<\/a><\/span><\/li>\n
  7. Okuyama T, Kyohara M, Terauchi Y, Shirakawa J. (2021\/6\/24) The Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling. Int J Mol Sci, 22(13):6817. [PubMed<\/a><\/span>]<\/li>\n
  8. Suzuki T, Hayashi M, Komatsu T, Tanioka A, Nagasawa M, Tanimura-Inagaki K, Rahman M.S, Masuda S, Yusa ., Sakai J, Shibata H, Inagaki T. (2021\/7\/15) Measurement of the nuclear concentration of \u03b1-ketoglutarate during adipocyte differentiation by using a fluorescence resonance energy transfer-based biosensor with nuclear localization signals. Endocr. J, 68(12):1429-1438. [PubMed<\/a>]<\/span><\/li>\n
  9. A Morita, Y Satouh, H Kosako, H Kobayashi, A Iwase, K Sato. (2021\/7\/15) Clathrin-mediated endocytosis is essential for the selective degradation of maternal membrane proteins and preimplantation development. Development, 148(14). [PubMed<\/a>]<\/span><\/li>\n
  10. Perez-Frances M, Gurp LV, Abate MV, Cigliola V, Furuyama K, Bru-Tari E, Oropeza D, Carreaux T, Fujitani Y, Thorel F, Herrera PL. (2021\/7\/22) Pancreatic Ppy-expressing \u03b3-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production. Nat Commun, 12(1):4458. [PubMed<\/span><\/a>]<\/li>\n
  11. Ohashi K, Chaleckis R. (2021\/8\/13) High levels of Tryptophan reduce cell wall or membrane stress tolerance in Saccharomyces cerevisiae. Biosci Biotechnol Biochem, 85(10):2131-2136. [PubMed<\/a><\/span>]<\/li>\n
  12. Shirakawa J. (2021\/8\/17) Translational research on human pancreatic \u03b2-cell mass expansion for the treatment of diabetes. Diabetol Int, 12(4):349-355. [PubMed<\/a><\/span>]<\/li>\n
  13. Yoshizawa Y, Hosojima M, Kabasawa H, Tanabe N, Miyachi A, Hamajima H, Mieno E, Kobayashi M, Kitamura T, Narita I, Saito A. (2021\/8\/28) Measurement of plasma glucagon levels using mass spectrometry in patients of type 2 diabetes on maintenance hemodialysis. Kidney Blood Press Res, 46(5):652-656. [PubMed<\/span><\/a>]<\/li>\n
  14. Mohan R, Jo S, Lockridge A, Ferrington DA, Murray K, Eschenlauer A, Bernal-Mizrachi E, Fujitani Y, Alejandro EU. (2021\/8\/30) OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1. Diabetes, 70(11):2608-2625. [PubMed<\/a><\/span>]<\/li>\n
  15. N Inoue, Y Satouh, I Wada. (2021\/9\/2) IZUMO family member 3, IZUMO3, is involved in male fertility through the acrosome formation. Mol Reprod Dev, 88(7):479-481. [PubMed<\/a><\/span>]<\/li>\n
  16. Terui S, Akamatsu R, Arai M, Inoue R, Okuyama T, Kyohara M, Li J, Tsuno T, Miyashita D, Togashi Y, Terauchi Y, Shirakawa J. (2021\/9\/17) Immediate Glucose-Lowering Effect After the First Administration of Dulaglutide: A Retrospective, Single-Center, Observational Study. Diabetes Ther, 12(11):2873-2889. [PubMed<\/a><\/span>]<\/li>\n
  17. Morio A, Tsutsumi R, Kondo T, Miyachi H, Kato T, Narasaki S, Satomi S, Nakaya E, Kuroda M, Sakaue H, Kitamura T, Tsutsumi YM. (2021\/9\/20) Leucine induces cardioprotection in vitro by promoting mitochondrial function via mTOR and Opa-1 signaling. Nutr Metab Cardiovasc Dis, 31(10):2979-2986. [PubMed<\/a><\/span>]<\/li>\n
  18. Zhao M-M, Lu J, Li S, Wang H, Cao X, Li Q, Shi T-T, Matsunaga K, Chen C, Huang H, Izumi T, and Yang J-K. (2021\/9\/23) Berberine is a novel insulin secretagogue targeting the KCNH6 potassium channel. Nat. Commun, 12(1):5616. [PubMed<\/a><\/span>]<\/li>\n
  19. Minami T, Shirakawa J, Hiiragi H, Yamada T, Suzuki Y, Shirabe S, Maeda H, Terauchi Y. (2021\/9\/26) Validity and reliability of the Japanese version of the diabetes knowledge test among in-patients with type 2 diabetes. J Diabetes Investig, 13(3):580-587. [PubMed<\/a><\/span>]<\/li>\n
  20. Shirakawa J. (2021\/9\/27) Pancreatic \u03b2-cell fate in subjects with COVID-19. J Diabetes Investig, 12(12):2126-2128. [PubMed<\/a><\/span>]<\/li>\n
  21. Wada E, Kobayashi M, Kohno D, Kikuchi O, Suga T, Matsui S, Yokota-Hashimoto H, Honzawa N, Ikeuchi Y, Tsuneoka H, Hirano T, Obinata H, Sasaki T, Kitamura T. (2021\/10\/9) Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice. J Nutr Biochem, 97:108811. [PubMed<\/a><\/span>]<\/li>\n
  22. Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K. (2021\/10\/20) Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol, 4(1):1204. [PubMed<\/a><\/span>]<\/li>\n
  23. Izumi T. (2021\/11\/6) In vivo roles of Rab27 and its effectors in exocytosis. Cell Struct Funct, 46(2):79-94.
    [    PubMed<\/a><\/span>]<\/li>\n
  24. Kato S, Arasaki K, Tokutomi N, Imai Y, Inoshita T, Hattori N, Sasaki T, Sato M, Wakana Y, Inoue H, Tagaya M. (2021\/11\/15) Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms. J Cell Sci, 134(22):jcs258699. [PubMed<\/a><\/span>]<\/li>\n
  25. Masubuchi Y, Ma J, Suzuki T, Kojima I, Inagaki T, Shibata H. (2021\/11\/19) T1R3 homomeric sweet taste receptor negatively regulates insulin-induced glucose 2 transport through G\u03b1s-mediated microtubules disassembly in 3T3-L1 adipocytes. Endocr J, 69(5):487-493. [PubMed<\/a><\/span>]<\/li>\n
  26. Yoshida N, Yamashita T, Osone T, Hosooka T, Shinohara M,Kitahama S, Sasaki K, Sasaki D,Yoneshiro T, Suzuki T, Emoto T, Saito Y. Ozawa G, Hirota Y, Kitaura Y, Shimomura Y, Okamatsu-Ogura Y, Saito M, Kondo A, Kajimura S, Inagaki T, Ogawa W, Yamada T, Hirata K.I. (2021\/11\/19) Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity. iScience, 24(11):103342. [PubMed<\/a><\/span>]<\/li>\n
  27. Morio A, Tsutsumi R, Satomi S, Kondo T, Miyoshi H, Kato T, Kuroda M, Kitamura T, Hara K, Saeki N, Sakaue H, Tsutsumi Y-M. (2021\/11\/20) Leucine imparts cardioprotective effects by enhancing mTOR activity and mitochondrial fusion in a myocardial ischemia\/reperfusion injury murine model. Diabetol Metab Syndr, 13(1):139. [PubMed<\/a><\/span>]<\/li>\n
  28. Fukaishi T, Nakagawa Y, Fukunaka A, Sato T, Hara A, Nakao K, Saito M, Kohno K, Miyatsuka T, Tamaki M, Matsuhisa M, Matsuoka T, Yamada T, Watada H, Fujitani Y. (2021\/12\/1) Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice. Diabetologia, 64(12):2803-2816. [PubMed<\/a><\/span>]<\/li>\n
  29. Kitakaze K, Oyadomari M, Zhang J, Hamada Y, Takenouchi Y, Tsuboi K, Inagaki M, Tachikawa M, Fujitani Y, Okamoto Y, Oyadomari S. (2021\/12\/1) ATF4-mediated transcriptional regulation protects against \u03b2-cell loss during endoplasmic reticulum stress in a mouse model. Mol Metab, 54:101338. [PubMed<\/a><\/span>]<\/li>\n
  30. Matsumura Y, Ito R, Yajima A, Yamaguchi R, Tanaka T, Kawamura T, Magoori K. Abe Y, Uchida A, Yoneshiro T, Hirakawa H, Zhang J, Arai M, Yang C, Yang G, Takahashi H, Fujihashi H, Nakaki R, Yamamoto S, Satoshi Ota S, Tsutsumi S, Inoue S.I, Kimura H, Wada Y, Kodama T, Inagaki T, Osborne T, Aburatani H, Node K, Sakai J. (2021\/12\/2) Nat Commun, 12(1):7045. [PubMed<\/a><\/span>]<\/li>\n
  31. Noguchi K, Yokozeki K, Tanaka Y, Suzuki Y, Nakajima K, Nishimura T, Goda N. (2021\/12\/27) Sima, a Drosophila homolog of HIF-1\u03b1, in fat body tissue inhibits larval body growth by inducing Tribbles gene expression. Genes Cells, 27(2):145-151. [PubMed<\/a><\/span>]<\/li>\n
  32. Uchiyama S, Yoshihara K, Kawanabe R, Hatada I, Koga K, Tsuda M. (2022\/1\/3) Stress-induced antinociception to noxious heat requires \u03b1 1A-adrenaline receptors of spinal inhibitory neurons in mice. Mol Brain, 15(1):6. [PubMed<\/a><\/span>]<\/li>\n
  33. Halperin F, Mezza T, Li P, Shirakawa J, Kulkarni RN, Goldfine AB. (2022\/1\/7) Insulin regulates arginine-stimulated insulin secretion in humans. Metabolism, 128:155117. [PubMed<\/span><\/a>]<\/li>\n
  34. Kondo Y, Ozawa A, Kohno D, Saito K, Buyandalai B, Yamada S, Horiguchi K, Nakajima Y, Shibusawa N, Harada A, Yokoo H, Akiyama H, Sasaki T, Kitamura T, Yamada M. (2022\/1\/9) The hypothalamic paraventricular 1 nucleus is the center of the hypothalamo-pituitary-thyroid axis for regulating thyroid hormone levels. Thyroid, 32(1):105-114. [PubMed<\/a><\/span>]<\/li>\n
  35. Inaba K, Ebihara K, Yoshino R, Sakuma C, Koiwai K, Takaya D, Watanabe C, Watanabe A, Kawashima Y, Fukuzawa K, Imamura R, Kojima H, Okabe T, Uemura N, Kasai S, Kanuka H, Nishimura T, Wanatabe K, Inoue H, Fujikawa Y, Honma T, Hirokawa T, Senda T, Niwa R. (2022\/2\/17)\u00a0 Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti. BMC Biol, 20(1):43. [PubMed<\/a><\/span>]<\/li>\n
  36. Mizukami M, Muraoka T, Shiozaki S, Tobita S, Yoshihara T. (2022\/2\/2) Near-Infrared Emitting Ir (III) Complexes Bearing a Dipyrromethene Ligand for Oxygen Imaging of Deeper Tissues In Vivo. Anal Chem, 94(6):2794-2802. [PubMed<\/a><\/span>]<\/li>\n
  37. Yoshihara T, Matsumura N, Tamura T, Shiozaki S, Tobita S. (2022\/2\/3) Intracellular and Intravascular Oxygen Sensing of Pancreatic Tissues Based on Phosphorescence Lifetime Imaging Microscopy Using Lipophilic and Hydrophilic Iridium (III) Complexes. ACS Sens, 7(2):545-554. [PubMed<\/a><\/span>]<\/li>\n
  38. Yamamoto Y, Ozamoto Y, Kobayashi M, Tezuka Y, Azuma C, Sekine O, Ito-Kobayashi J, Washiyama M, Oe Y, Iwanishi M, Togawa T, Hagiwara A, Kitamura T, Shimatsu A and Kashiwagi A. (2022\/2\/6) Effects of a new 75 g glucose- and high fat-containing cookie meal test on postprandial glucose and triglyceride excursions in morbidly obese patients. Endocr J, 69(6):689-703. [PubMed<\/a><\/span>]<\/li>\n
  39. Perez-Frances M, Abate MV, Baronnier D, Scherer PE, Fujitani Y, Thorel F, Herrera PL. (2022\/2\/15) Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells. Cell Rep, 38(7):110377. [PubMed<\/a><\/span>]<\/li>\n
  40. Watanave M, Takahashi N, Hosoi N, Konno A, Yamamoto H, Yasui H, Kawachi M, Horii T, Matsuzaki Y, Hatada I, Hirai H. (2022\/2\/15) Protein kinase C\u03b3 in cerebellar Purkinje cells regulates Ca 2+-activated large-conductance K + channels and motor coordination. Proc Natl Acad Sci U S A, 119(7):e2113336119. [PubMed<\/a><\/span>]<\/li>\n
  41. Li J, Inoue R, Togashi Y, Okuyama T, Satoh A, Kyohara M, Nishiyama K, Tsuno T, Miyashita D, Kin T, Shapiro AMJ, Chew RSE, Teo AKK, Oyadomari S, Terauchi Y, Shirakawa J. (2022\/3\/1) Imeglimin Ameliorates \u03b2-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway. Diabetes, 71(3):424-439. [PubMed<\/a><\/span>]<\/li>\n
  42. Y satouh. (2022\/3\/1) The phenotype of PLC\u03b61-deficient mice. Reproduction, 164(1):F21-F28. [PubMed<\/a><\/span>]<\/li>\n
  43. Hirano H, Shirakawa J. (2022\/3\/22) Recent developments in Phos-tag electrophoresis for the analysis of phosphoproteins in proteomics. Expert Rev Proteomics, 19(2):103-114. [PubMed<\/a><\/span>]<\/li>\n
  44. Haraoka Y, Akieda Y, Nagai Y, Mogi C, Ishitani T. (2022\/3\/18 ) Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis. Nat Commun, 13(1):1417. [PubMed<\/a><\/span>]<\/li>\n
  45. \u5317\u6751\u5fe0\u5f18. (2021\/4\/1) \u30b0\u30eb\u30ab\u30b4\u30f3\uff08\u81b5\u03b1\u7d30\u80de\uff09\u306f\u3069\u3053\u307e\u3067\u308f\u304b\u3063\u305f\u304b\u3002 \u533b\u5b66\u51fa\u7248, 38-44.<\/li>\n
  46. \u5800\u5c45\u62d3\u90ce\u3001\u68ee\u7530\u7d14\u4ee3\u3001\u7551\u7530\u51fa\u7a42. (2021\/4\/12) \u72d9\u3063\u305f\u30a8\u30d4\u30b2\u30ce\u30e0\u304c\u5909\u7570\u3057\u305f\u75be\u60a3\u30e2\u30c7\u30eb\u52d5\u7269\u306e\u958b\u767a. BIO Clinica, 36(5)103-108.<\/li>\n
  47. \u5800\u5c45\u62d3\u90ce\u3001\u68ee\u7530\u7d14\u4ee3\u3001\u7551\u7530\u51fa\u7a42. (2021\/4\/25) \u30a8\u30d4\u30b2\u30ce\u30e0\u7de8\u96c6\u306b\u3088\u308b\u5148\u5929\u6027\u75be\u60a3\u30e2\u30c7\u30eb\u52d5\u7269\u306e\u4f5c\u88fd. \u907a\u4f1d\u5b50\u533b\u5b66MOOK, 36,51-57.<\/li>\n
  48. \u5800\u5c45\u62d3\u90ce\u3001\u68ee\u7530\u7d14\u4ee3\u3001\u7551\u7530\u51fa\u7a42. (2021\/5\/21) \u30a8\u30d4\u30b2\u30ce\u30e0\u7de8\u96c6\u306b\u3088\u308b\u75be\u60a3\u30e2\u30c7\u30eb\u52d5\u7269\u306e\u4f5c\u88fd. \u7d30\u80de, 53,42-46.<\/li>\n
  49. \u4f50\u3005\u6728\u4f38\u96c4\uff0c\u5c0f\u7530\u53f8\uff0c\u4f50\u85e4\u4fca\u6717. (2021\/11\/1) \u8178\u30aa\u30eb\u30ac\u30ce\u30a4\u30c9. \u79d1\u5b66\u8a55\u8ad6\u793e, 471-477.<\/li>\n
  50. \u5317\u6751\u5fe0\u5f18. (2022\/2\/25) \u7cd6\u5c3f\u75c5\u306e\u8a3a\u65ad\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u6e2c\u5b9a. \u533b\u6b6f\u85ac\u51fa\u7248, 30-39.<\/li>\n
  51. \u85e4\u8c37\u4e0e\u58eb\u592b. (2022\/3\/1) \u4ee3\u8b1d\u30fb\u6804\u990a\u306e\u7570\u5e38\u3000\u7dcf\u8ad6. \u671d\u5009\u3000\u5185\u79d1\u5b66\u3000\u7b2c12\u7248, iV-348-352.<\/li>\n<\/ol>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Kawanabe R, Yoshihara K, Hatada I, Tsuda M. (2021\/5\/10) Activation of spinal dorsal horn astrocytes by noxious […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":4759,"menu_order":141,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-12270","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/12270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12270"}],"version-history":[{"count":78,"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/12270\/revisions"}],"predecessor-version":[{"id":12648,"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/12270\/revisions\/12648"}],"up":[{"embeddable":true,"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/4759"}],"wp:attachment":[{"href":"https:\/\/www.imcr.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}