| 1951 March |
The Endocrine Research Facility of medicine was founded in Gunma University School. |
| 1951 April |
First Department (Organ Functions) was started. Research Building 1was constructed. |
| 1952 April |
Second Department (Functional Morphology) was started. |
| 1953 April |
Third Department (Experimental Biology) was started. |
| 1954 May |
Research Building 2 was constructed. |
| 1955 July |
Second Department was shifted to Department of Biological Functions. Forth Department (Morphology) was started. |
| 1957 April |
Fifth Department (Physical Biochemistry) was started. |
| 1963 March |
The Facility was graded up to the Institute of Endocrinology in the Gunma University. |
| 1963 April |
The Institute consisted of First Research Dept.(Morphology), Second Research Dept.(Physiology), Third Research Dept.(Comparative Endocrinology), Fourth Research Dept.(Physical Biochemistry), and Fifth Research Dept.(Pharmaceutical Chemistry). |
| 1966 April |
Sixth Research Department (Protein Chemistry) was started. |
| 1967 March |
Headquerter Building was constructed. |
| 1972 May |
Research Facility (Hormone Assay Center) was started. |
| 1994 June |
The Institute was renovated to the Institute for Molecular and Cellular Regulation, and Hormone Assay Center to the Biosignal Research Center. |
| 2002 October |
Accepted as a Center for the 21st COE Program. |
| 2004 January |
Construction of new building and renovation of old building were completed. |
| 2004 December |
Biosignal Research Center is changed to Biosignal Genome Resource Center. |
| 2007 April |
The Institute for Molecular and Cellular Regulation was reorganized and a new research center, namely the Research Center for Metabolic Signals was built. |
| 2007 June |
Accepted as a center for the Global COE Program. |
| 2009 June |
Accepted as a Collaborative Research Center for endocrinology and metabolism. |
| 2014 October |
Associated with Gunma University Initiative for Advanced Research (Research Program for Signal Transduction). |
| 2016 April |
Colaborative Research Center for Endcrinology and Metabolism was renewed |
