Professor：SATO Miyuki
m-sato*gunma-u.ac.jp
(*=@)
Lab website
http://makukinou.showa.gunma-u.ac.jp/index.html
Member
Professor: SATO Miyuki
Assistant Professor: SEKIMOTO Takayuki
Assistant Professor: SASAKI Taeko
Technical Officer: USHIGOME Takeshi
JSPS Research Fellow: NORIZUKI Takuya
Technical Assistant: KOIKE Noriko
Technical Assistant: YAMASHITA Haruka
Graduate Student: UESUGI Rie
Technical Assistant: NAKAZAWA Saya
Technical Assistant: MASUDA Nene
Research
Eukaryotic cells are composed of many membrane-bound organelles, and the shape, composition, and functions of these organelles are dynamically regulated under various conditions through membrane trafficking. The aim of our research is to understand the molecular mechanisms of membrane trafficking and its physiological roles in animal development. We are especially interested in mechanisms and functions of endocytosis and autophagy in C. elegans embryos.
On-going projects
- Selective degradation of paternal mitochondria by autophagy.
- Endocytic degradation of maternal membrane proteins in embryos.
Keywords
Membrane trafficking, Autophagy, Endocytosis, Lysosome, Metabolism, Development, C. elegans, Fertilization, Mitochondria
Select References
- Sasaki T and Sato M. (2021) Biochim Biophys Acta Gen Subj 1865: 129886.
- Saegusa K, et al. (2018) J Cell Biol 217: 2073-2085.
- Sato M, et al. (2018) Nat Cell Biol 20: 81-91.
- Sato M, et al. (2014) Development 141: 1324-1331.
- Sato M and Sato K. (2011) Science 334: 1141-1144.
