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群馬大学 生体調節研究所

アクセス

Developmental Biology and Metabolism

Fujitani

Professor:Yohio Fujitani
fujitani*gunma-u.ac.jp
(*=@)
Lab website
http://tou-taisha.imcr.gunma-u.ac.jp/index.html

 

 

Member

Professor: Yoshio Fujitani
Associate Professor: Takashi Sato
Assistant Professor: Ayako Fukunaka
Assistant Professor: Yuko Nakagawa
Chief Technician: Masayuki Tobo
Post Doctoral Fellow: Azumi Noguchi
Assistant Technician: Asuka Suda
Assistant Technician: Yasuko Tamura
Medical Student : Yoichiro Nishikawa

Research

The dysfunction of pancreatic b cells, brown adipocytes, and enterocytes can cause diabetes and metabolic syndrome. Our goal is to elucidate the molecular mechanism involved in the maintenance of homeostasis of these higher-order function cells, which is the key to glucose metabolism. We aim to elucidate the mechanism of cellular homeostasis, from a variety of viewpoints, including developmental biology, zinc biology, autophagy, and cell polarity, by effectively utilizing genetically engineered mice. Furthermore, using our findings from basic medical research, we aim to establish a groundbreaking treatment for diabetes and obesity.
ホームページ ポンチ絵改訂版2(E)

 

On-going projects

  • Research on the developmental biology of pancreatic b cells
  • Functional analysis of autophagy in lifestyle-associated diseases
  • Analysis of zinc transporters involved in the beiging of adipocytes
  • Screening and functional analysis of molecules involved in the regulation of enterocytes

Keywords

diabetes, glucose metabolism, developmental biology, pancreatic  cells, genetically engineered mice, brown adipocytes, zinc biology, autophagy, enterocytes

Select References

  1. Shigihara N. et al. (2014) J Clin Invest. 124(8):3634-44.
  2. Sato T. et al. (2014) J Cell Sci. 127(Pt 2):422-31
  3. Tamaki M. et al. (2013) J Clin Invest. 123(10):4513-24
  4. Ebato C. et al. (2008) Cell Metab. 8(4):325-32
  5. Sato T. et al. (2007) Nature 448(7151):366-9.

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