Professor: Yoshio Fujitani
Associate Professor: Takashi Sato
Assistant Professor: Ayako Fukunaka
Assistant Professor: Yuko Nakagawa
Chief Technician: Masayuki Tobo
Post Doctoral Fellow: Azumi Noguchi
Assistant Technician: Asuka Suda
Assistant Technician: Yasuko Tamura
Medical Student : Yoichiro Nishikawa
The dysfunction of pancreatic b cells, brown adipocytes, and enterocytes can cause diabetes and metabolic syndrome. Our goal is to elucidate the molecular mechanism involved in the maintenance of homeostasis of these higher-order function cells, which is the key to glucose metabolism. We aim to elucidate the mechanism of cellular homeostasis, from a variety of viewpoints, including developmental biology, zinc biology, autophagy, and cell polarity, by effectively utilizing genetically engineered mice. Furthermore, using our findings from basic medical research, we aim to establish a groundbreaking treatment for diabetes and obesity.
- Research on the developmental biology of pancreatic b cells
- Functional analysis of autophagy in lifestyle-associated diseases
- Analysis of zinc transporters involved in the beiging of adipocytes
- Screening and functional analysis of molecules involved in the regulation of enterocytes
diabetes, glucose metabolism, developmental biology, pancreatic cells, genetically engineered mice, brown adipocytes, zinc biology, autophagy, enterocytes
- Shigihara N. et al. (2014) J Clin Invest. 124(8):3634-44.
- Sato T. et al. (2014) J Cell Sci. 127(Pt 2):422-31
- Tamaki M. et al. (2013) J Clin Invest. 123(10):4513-24
- Ebato C. et al. (2008) Cell Metab. 8(4):325-32
- Sato T. et al. (2007) Nature 448(7151):366-9.