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群馬大学 生体調節研究所

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発表論文

遺伝生化学分野(泉哲郎)

No. Year Title Author Corresponding Journal Vol. Pages
1 2013 Activin receptor-like kinase 7 suppresses lipolysis to accumulate fat in obesity through downregulation of peroxisome proliferator-activated receptor γ and C/EBPα Yogosawa S, Mizutani S, Ogawa Y, and Izumi T Izumi T Diabetes 62 115-123
2 2013 The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane. Wang H, Ishizaki R, Xu J, Kasai K, Kobayashi E, Gomi H, Izumi T Izumi T Mol. Biol. Cell 24 319-30
3 2013 Roles of activin receptor-like kinase 7 signaling and its target, peroxisome proliferator-activated receptor γ, in lean and obese adipocytes. Yogosawa S and Izumi T Izumi T Adipocyte 2 246-250
4 2013 TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis. Fujimoto Y, Nakagawa Y, Satoh A, Okuda K, Shingyouchi A, Naka A, Matsuzaka T, Iwasaki H, Kobayashi K, Yahagi N, Shimada M, Yatoh S, Suzuki H, Yogosawa S, Izumi T, Sone H, Urayama O, Yamada N, Shimano H Nakagawa Y Endocrinology 154 3577-3588
5 2015 Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts. Shimada-Sugawara M, Sakai E, Okamoto K, Fukuda M, Izumi T, Yoshida N, and Tsukuba T Tsukuba T Sci. Rep. 5 9620
6 2015 PI3K regulates endocytosis after insulin secretion via signaling crosstalk between Arf6 and Rab27a. Yamaoka M, Ando T, Terabayashi T, Okamoto M, Takei M, Nishioka T, Kaibuchi K, Matsunaga K, Ishizaki R, Izumi T, Niki I, Ishizaki T, and Kimura T Kimura T J. Cell Sci. 129 637-649
7 2016 Granuphilin exclusively mediates functional granule docking to the plasma membrane. Mizuno K, Fujita T, Gomi H, and Izumi T Izumi T Sci. Rep. 6 23909
8 2017 Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2. Matsunaga K, Taoka M, Isobe T, and Izumi T Izumi T J. Cell Sci. 130 541-550
9 2017 Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa. Fan F, Matsunaga K, Wang H, Ishizaki R, Kobayashi E, Kiyonari H, Mukumoto Y, Okunishi K, and Izumi T Izumi T Elife 6 e26174
10 2018 Insulin regulates lipolysis and fat mass in adipocytes by upregulating growth/differentiation factor 3 in adipose macrophages. Bu Y, Okunishi K, Yogosawa S, Mizuno K, Irudayam MJ, Brown CW, and Izumi T Izumi T Diabetes 67 1761-1772
11 2018 Response to comment on Bu et al.: Insulin regulates lipolysis and fat mass in adipocytes by upregulating growth/differentiation factor 3 in adipose macrophages. Diabetes 2018;67:1761-1772. Izumi T Izumi T Diabetes 67 e2-e3
12 2019 Coixol amplifies glucose-stimulated insulin secretion via cAMP mediated signaling pathway. Hameed A, Hafizur RM, Kahn MI, Jawed A, Wang H, Zhao M, Matsunaga K, Izumi T, Siddiqui S, Khan F, Adhikari A, and Sharma KR Hafizur RM Eur. J. Pharmacol. 858 172514
13 2020 Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses. Okunishi K, Wang H, Suzukawa M, Ishizaki R, Kobayashi E, Kihara M, Abe T, Miyazaki J, Horie M, Saito A, Saito H, Nakae S, and Izumi T Okunishi K / Izumi T J. Clin. Invest. 130 3919-3935
14 2020 Melanophilin accelerates granule fusion without predocking to the plasma membrane. Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, and Izumi T Izumi T Diabetes 69 2655-2666
15 2021 Berberine is a novel insulin secretagogue targeting the KCNH6 potassium channel. Zhao M-M, Lu J, Li S, Wang H, Cao X, Li Q, Shi T-T, Matsunaga K, Chen C, Huang H, Izumi T, and Yang J-K Yang J-K Nat. Commun. 12 5616
16 2021 In vivo roles of Rab27 and its effectors in exocytosis. Izumi T Izumi T Cell Struct. Funct. 46 79-94

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