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群馬大学 生体調節研究所

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発表論文

臓器病態内科学分野(倉林正彦,大山善昭)

No. Year Title Author Corresponding Journal Vol. Pages
1 2013 A critical role of fatty acid binding protein 4 and 5 (FABP4|5) in the systemic response to fasting. Syamsunarno MR, Iso T, Hanaoka H, Yamaguchi A, Obokata M, Koitabashi N, Goto K, Hishiki T, Nagahata Y, Matsui H, Sano M, Kobayashi M, Kikuchi O, Sasaki T, Maeda K, Murakami M, Kitamura T, Suematsu M, YoshitoTsushima, Endo K, Hotamisligil GS, Kurabayashi M. Iso T PLoS ONE 8 e79386
2 2013 Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice. Sunaga H, Matsui H, Ueno M, Maeno T, Iso T, Syamsunarno MR, Anjo S, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M. Yokoyama T Nat Commun 4 2563
3 2013 Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle. so T, Maeda K, Hanaoka H, Suga T, Goto K, Syamsunarno MR, Hishiki T, Nagahata Y, Matsui H, Arai M, Yamaguchi A, Abumrad NA, Sano M, Suematsu M, Endo K, Hotamisligil GS, Kurabayashi M. Iso T Arterioscler Thromb Vasc Biol. 33 :2549-57
4 2013 Peroxisome proliferator-activated receptor-γ in capillary endothelia promotes fatty acid uptake by heart during long-term fasting. Goto K, Iso T, Hanaoka H, Yamaguchi A, Suga T, Hattori A, Irie Y, Shinagawa Y, Matsui H, Syamsunarno MR, Matsui M, Haque A, Arai M, Kunimoto F, Yokoyama T, Endo K, Gonzalez FJ, Kurabayashi M. Iso T J Am Heart Assoc. 2 e004861
5 2013 Estimated glomerular filtration rate and proteinuria are separately and independently associated with the prevalence of atrial fibrillation in general population. Ohyama Y, Imai M, Kurabayashi M. Ohyama Y PLoS ONE 8 e79717
6 2013 Palmitic acid induces osteoblastic differentiation in vascular smooth muscle cells through ACSL3 and NF-κB, novel targets of eicosapentaenoic acid Kageyama A1, Matsui H, Ohta M, Sambuichi K, Kawano H, Notsu T, Imada K, Yokoyama T, Kurabayashi M. Kawano H PLoS ONE 8 e68197
7 2014 Hydrogen sulfide: a new regulator of osteoclastogenesis? Kurabayashi M Kurabayashi M Arterioscler Thromb Vasc Biol. 34 471-3.
8 2014 Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress. Syamsunarno MR, Iso T, Yamaguchi A, Hanaoka H, Putri M, Obokata M, Sunaga H, Koitabashi N, Matsui H, Maeda K, Endo K, Tsushima Y, Yokoyama T, Kurabayashi M. Iso T PLoS ONE 9 e90825
9 2015 Effects of adding intravenous nicorandil to standard therapy on cardiac sympathetic nerve activity and myocyte dysfunction in patients with acute decompensated heart failure. Kasama S, Toyama T, Funada R, Takama N, Koitabashi N, Ichikawa S, Suzuki Y, Matsumoto N, Sato Y, Kurabayashi M Kasama S Eur J Nucl Med Mol Imaging 42 761-70
10 2015 CD36 is indispensable for thermogenesis under conditions of fasting and cold stress. Putri M, Syamsunarno MR, Iso T, Yamaguchi A, Hanaoka H, Sunaga H, Koitabashi N, Matsui H, Yamazaki C, Kameo S, Tsushima Y, Yokoyama T, Koyama H, Abumrad NA, Kurabayashi M Kurabayashi M Biochem Biophys Res Commun. 457 520-5
11 2015 Effects of statin therapy on cardiac sympathetic nerve activity and left ventricular remodeling in patients with chronic heart failure: a propensity score-matched analysis. Sano H, Kasama S, Fujimoto S, Toyama T, Takama N, Koitabashi N, Ichikawa S, Suzuki Y, Matsumoto N, Sato Y, Kurabayashi M. Kasama S Medicine 93 e214
12 2015 Serial ¹²³I-metaiodobenzylguanidine imaging predicts the risk of sudden cardiac death in patients with chronic heart failure. Kasama S, Toyama T, Kurabayashi M. Kurabayashi M Int J Cardiol 179 Mar-82
13 2015 Extremely Low Levels of Serum Uric Acid Are Associated With Endothelial Dysfunction in Humans. Iso T, Kurabayashi M Iso T Circ J.  79 i978-980
14 2015 Alendronate inhalation ameliorates elastase-induced pulmonary emphysema in mice by induction of apoptosis of alveolar macrophages. Ueno M, Maeno T, Nishimura S, Ogata F, Masubuchi H, Hara K, Yamaguchi K, Aoki F, Suga T, Nagai R, Kurabayashi M. Kurabayashi, M Nat. Commun  6 6332
15 2015 A Risk Score with Additional Four Independent Factors to Predict the Incidence and Recovery from Metabolic Syndrome: Development and Validation in Large Japanese Cohorts. Obokata M, Negishi K, Ohyama Y, Okada H, Imai K, Kurabayashi M.   Kurabayashi M PLoS ONE 10 e0133884
16 2016 Lipoprotein(a) is a risk factor for aortic and mitral valvular stenosis in peripheral arterial disease. Hojo Y, Kumakura H, Kanai H, Iwasaki T, Ichikawa S, Kurabayashi M. Kumakura H Eur Heart J Cardiovasc Imaging  17 292-297
17  2016  Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Krüppel-Like Factor 4 (AMPK/KLF4) Signaling.  Sunaga H, Matsui H, Anjo S, Syamsunarno MR, Koitabashi N, Iso T, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.  Kurabayashi M  J Am Heart Assoc  5  e004014
18  2016  Ventricular-Arterial Coupling and Exercise-Induced Pulmonary Hypertension During Low-Level Exercise in Heart Failure With Preserved or Reduced Ejection Fraction.  Obokata M, Nagata Y, Kado Y, Kurabayashi M, Otsuji Y, Takeuchi M.  Takeuchi M  J Card Fail  23  216-220
19  2016  Relation Between Echocardiogram-Based Cardiac Parameters and Outcome in Heart Failure With Preserved and Reduced Ejection Fraction.  Obokata M, Takeuchi M, Negishi K, Ohte N, Izumo M, Yamashita E, Ebato, Yuda S, Kurabayashi M, Nakatani S  Takeuchi M  Am J Cardiol 118  1356-1362
20  2016  Fibroblast growth factor 23 inhibits osteoblastic gene expression and induces osteoprotegerin in vascular smooth muscle cells.  Nakahara T, Kawai-Kowase K, Matsui H, Sunaga H, Utsugi T, Iso T, Arai M, Tomono S, Kurabayashi M  Kurabayashi M  Atherosclerosis 253  102-110
21  2016  Cumulative Burden of Myocardial Dysfunction in Cardiac Amyloidosis Assessed Using Four-Chamber Cardiac Strain  Kado Y, Obokata M, Nagata Y, Ishizu T, Addetia K, Aonuma K, Kurabayashi M, Lang RM, Takeuchi M, Otsuji Y  Takeuchi M  J Am Soc Echocardiogr  29  1092-1099
22 2016  Direct comparison of cardiac magnetic resonance feature tracking and 2D/3D echocardiography speckle tracking for evaluation of global left ventricular strain.  Obokata M, Nagata Y, Wu VC, Kado Y, Kurabayashi M, Otsuji Y, Takeuchi M  Takeuchi M  Eur Heart J Cardiovasc Imaging  17  525-32
23 2016  Usefulness of Cardiac Sympathetic Nerve Imaging Using (123)Iodine-Metaiodobenzylguanidine Scintigraphy for Predicting Sudden Cardiac Death in Patients With Heart Failure.  Kasama S, Toyama T, Kurabayashi M  Kasama S  Int Heart J.  57  140-144
24 2016  Comparative effects of long-acting and short-acting loop diuretics on cardiac sympathetic nerve activity in patients with chronic heart failure.  Matsuo Y, Kasama S, Toyama T, Funada R, Takama N, Koitabashi N, Ichikawa S, Suzuki Y, Matsumoto N, Sato Y, Kurabayashi M  Matsuo Y  Open Heart  3  e000276.
25 2016  Myocardial scintigraphic evidence of Kounis syndrome: what is the aetiology of acute coronary syndrome?  Goto K, Kasama S, Sato M, Kurabayashi M  Kasama S  Eur Heart J  37  1157
26 2016  Prognostic value of myocardial perfusion single photon emission computed tomography for major adverse cardiac cerebrovascular and renal events in patients with chronic kidney disease: results from first year of follow-up of the Gunma-CKD SPECT multicenter study.  Kasama S, Toyama T, Sato M, Sano H, Ueda T, Sasaki T, Nakahara T, Higuchi T, Tsushima Y, Kurabayashi M.  Kasama S  Eur J Nucl Med Mol Imaging 43  302-311
27 2016  Atypical Fast-Slow Atrioventricular Nodal Reentrant Tachycardia Incorporating a “Superior” Slow Pathway: A Distinct Supraventricular Tachyarrhythmia.  Kaneko Y, Naito S, Okishige K, Morishima I, Tobiume T, Nakajima T, Irie T, Ota M, Iijima T, Iizuka T, Tamura M, Tamura S, Saito A, Igawa O, Kato R, Matsumoto K, Suzuki F, Kurabayashi M  Kaneko Y  Circulation  133  114-123
28 2016  Effect of Sex Differences on the Association Between Stroke Risk and Left Atrial Anatomy or Mechanics in Patients With Atrial Fibrillation.  Yoshida K, Obokata M, Kurosawa K, Sorimachi H, Kurabayashi M, Negishi K  Negishi K  Circ Cardiovasc Imaging  9  e004999
29

2017

 

Incremental Prognostic Value of Ventricular-Arterial Coupling over Ejection Fraction in Patients with Maintenance Hemodialysis. Obokata M, Kurosawa K, Ishida H, Ito K, Ogawa T, Ando Y, Kurabayashi M, Negishi K. Negishi K J Am Soc Echocardiogr. 30 444-453
30 2017  Importance of compensatory heart rate increase during myocardial ischemia to preserve appropriate oxygen kinetics. Yoshida S, Adachi H, Murata M, Tomono J, Oshima S, Kurabayashi M. Adachi H  J Cardiol. 70 250-254
31 2017 Glucose fluctuation and the resultant endothelial injury are correlated with pancreatic β cell dysfunction in patients with coronary artery disease. Murata M, Adachi H, Oshima S, Kurabayashi M. Murata M Diabetes Res Clin Pract. 131 107-115
32 2017 Association Between Circulating Ketone Bodies and Worse Outcomes in Hemodialysis Patients. Obokata M, Negishi K, Sunaga H, Ishida H, Ito K, Ogawa T, Iso T, Ando Y, Kurabayashi M. Negishi K J Am Heart Assoc 6 e006885
33 2017 Comparative effects of long and short-acting loop diuretics on mortality in patients with chronic heart failure. Kasama S, Toyama T, Kurabayashi M Kasama S Int J Cardiol 244 242-244
34

2017

 

Serum levels of fatty acid binding protein 4 and fat metabolic markers in relation to catecholamines following exercise. Iso T, Sunaga H, Matsui H, Kasama S, Oshima N, Haruyama H, Furukawa N, Nakajima K, Machida T, Murakami M, Yokoyama T, Kurabayashi M Iso T Clin Biochem. 50 896-902
35 2017 Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice. Umbarawan Y, Syamsunarno MRAA, Obinata H, Yamaguchi A, Sunaga H, Matsui H, Hishiki T, Matsuura T, Koitabashi N, Obokata M, Hanaoka H, Haque A, Kunimoto F, Tsushima Y, Suematsu M, Kurabayashi M, Iso T Iso T Metabolism 77 47-57
36 2018 Identification and quantification of plasma calciprotein particles with distinct physical properties in patients with chronic kidney disease. Miura Y, Iwazu Y, Shiizaki K , Akimoto T , Kotani K , Kurabayashi M , Kurosu H & Kuro-o M Kuro-o M Sci Rep. 8 1256
37 2018 Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: Evidence from fatty acid binding protein-4 and -5 knockout mice. Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Yamaguchi A, Hanaoka H, Hishiki T, Nagahata-Naito Y, Obinata H, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T. Iso .T. Cardiovasc. Res.   e006885.
38 2018 Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure. Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Obinata H, Yamaguchi A, Hanaoka H, Hishiki T, Hayakawa N, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T Kurabayashi M Sci Rep. 8 12035
39

2018

 

CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting. Iso T, Haruyama H, Sunaga H, Matsui H, Matsui M, Tanaka R, Umbarawan Y, Syamsunarno MRAA, Putri M, Yamaguchi A, Hanaoka H, Negishi K, Yokoyama T, Kurabayashi M Iso .T. Physiol Rep 6 e13884
40 2018 Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption. Shrestha S, Sunaga H, Hanaoka H, Yamaguchi A, Kuwahara S, Umbarawan Y, Nakajima K, Machida T, Murakami M, Saito A, Tsushima Y, Kurabayashi M, Iso T Kurabayashi M Sci Rep. 8 16451
41 2018 Achieving LDL cholesterol target levels <1.81 mmol/L may provide extra cardiovascular protection in patients at high risk: Exploratory analysis of the Standard Versus Intensive Statin Therapy for Patients with Hypercholesterolaemia and Diabetic Retinopathy study. Itoh H, Komuro I, Takeuchi M, Akasaka T, Daida H, Egashira Y, Fujita H, Higaki J, Hirata KI, Ishibashi S, Isshiki T, Ito S, Kashiwagi A, Kato S, Kitagawa K, Kitakaze M, Kitazono T, Kurabayashi M, Miyauchi K, Murakami T, Murohara T, Node K, Ogawa S, Saito Y, Seino Y, Shigeeda T, Shindo S, Sugawara M, Sugiyama S, Terauchi Y, Tsutsui H, Ueshima K, Utsunomiya K, Yamagishi M, Yamazaki T, Yo S, Yokote K, Yoshida K, Yoshimura M, Yoshimura N, Nakao K, Nagai R; EMPATHY Investigators Ito. H Diabetes Obes Metab   13575
42 2019 Assessment of therapeutic effects of statin on cardiac sympathetic nerve activity and cardiac events in patients with ischemic cardiomyopathy and mild to moderate heart failure. Kasama S, Toyama T, Suzuki S, Ito Y, Matsumoto N, Kurabayashi M, Kasahara M. Kasama S Nucl Med Commun 40 159-168
43 2019 Enhanced closed-state inactivation of mutant cardiac sodium channels (SCN5A N1541D and R1632C) through different mechanisms. Dharmawan T, Nakajima T, Iizuka T, Tamura S, Matsui H, Kaneko Y, Kurabayashi M Nakajima T, J Mol Cell Cardiol. 130 88-95
44 2019 Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice. Iso T, Haruyama H, Sunaga H, Matsui M, Matsui H, Tanaka R, Umbarawan Y, Syamsunarno MRAA, Yokoyama T, Kurabayashi M Iso .T. BMC Physiol 19 1
45 2019 Sex differences in left ventricular afterload and diastolic function are independent from the aortic size. Sorimachi H, Kurosawa K, Yoshida K, Obokata M, Noguchi T, Naka M, Tange S, Kurabayashi M, Negishi K. Negishi K. PLoS One. 14 e0214907
46 2019 Association of Uric Acid with Incident Metabolic Syndrome in a Japanese General Population. Sumiyoshi H, Ohyama Y, Imai K, Kurabayashi M, Saito Y, Nakamura T.   Int Heart J. 60 830-835
47 2019 Superior-type fast-slow atrioventricular nodal reentrant tachycardia with a 2:1 atrioventricular block. Kaneko Y, Nakajima T, Tamura S, Kurabayashi M.   J Cardiovasc Electrophysiol. 30 1696-1698
48 2019 Role of the voltage sensor module in Nav domain IV on fast inactivation in sodium channelopathies: The implication of closed-state inactivation. Nakajima T, Kaneko Y, Dharmawan T, Kurabayashi M.   Channels (Austin). 13 331-343.
49 2019 Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts. Sunaga H, Koitabashi N, Iso T, Matsui H, Obokata M, Kawakami R, Murakami M, Yokoyama T, Kurabayashi M.   Sci Rep. 9 11841
50 2019 Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension. Seki M, Furukawa N, Koitabashi N, Obokata M, Conway SJ, Arakawa H, Kurabayashi M  Koitabashi N PLoS One. 14 e0220795
51 2019 Assessment of therapeutic effects of statin on cardiac sympathetic nerve activity after reperfusion therapy in patients with first ST-segment elevation myocardial infarction and normal low-density lipoprotein cholesterol. Takahashi S, Kasama S, Toyama T, Suzuki S, Ito Y, Nakata T, Kasahara M, Kurabayashi M.   J Nucl Cardiol.   x
52 2020 The relationship between antecedent creatinine decreases and outcomes in patients undergoing hemodialysis. Harada T, Sorimachi H, Obokata M, Sunaga H, Ishida H, Ito K, Ogawa T, Ando Y, Kurabayashi M, Negishi K.   Hemodial Int. 24 89-98
53 2020 Short-term exposure to ambient fine particulate matter and out-of-hospital cardiac arrest: a nationwide case-crossover study in Japan. Zhao B, Johnston FH, Salimi F, Kurabayashi M, Negishi K.   Lancet Planet Health. 4 e15-e23
54 2020 Early Lifestyle Modification Is an Essential Step in Telemedicine for Heart Failure. Koitabashi N, Obokata M, Kurabayashi M.   Circ. J 84 380-381
55 2020 Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy. Umbarawan Y, Kawakami R, Syamsunarno MRAA, Koitabashi N, Obinata H, Yamaguchi A, Hanaoka H, Hishiki T, Hayakawa N, Sunaga H, Matsui H, Kurabayashi M, Iso T. Iso T Sci Rep. 10 20809
56 2020 Independent and incremental prognostic value of semiquantitative measures of tricuspid regurgitation severity in heart failure with preserved ejection fraction. Harada T, Obokata M, Omote K, Iwano H, Ikoma T, Okada K, Yoshida K, Kato T, Kurosawa K, Nagai T, Negishi K, Anzai T, Kurabayashi M. M. Obokata Eur Heart J Cardiovasc Imaging   jeaa264
57 2020 Pathophysiological role of fatty acid-binding protein 4 in Asian patients with heart failure and preserved ejection fraction. Harada T, Sunaga H, Sorimachi H, Yoshida K,  Kato T, Kurosawa K, Nagasaka T, Koitabashi N, Iso T,  Kurabayashi M, Obokata M M. Obokata ESC Heart Fail. 7 4256-66
58 2021 Reduced current density, partially rescued by mexiletine, and depolarizing shift in activation of SCN5A W374G channels as a cause of severe form of Brugada syndrome. Nakajima T, Dharmawan T, Kawabata-Iwakawa R, Tamura S, Hasegawa H, Kobari T, Ota M, Tange S, Nishiyama M, Kaneko Y, Kurabayashi M Iso T Ann Noninvasive Electrocardiol   e12828
59 2021 Prognostic impact of elevated fatty acid-binding protein 1 in patients with heart failure Kagami K, Sunaga H, Sorimachi H, Harada T, Yoshida K, Kato T, Kurosawa K, Kawakami R, Koitabashi N, Iso T, Adachi T, Kurabayashi M, Obokata M. Obokata M ESC Heart Fail. 8 1494-1501
60 2021 FABP5 Is a Sensitive Marker for Lipid-Rich Macrophages in the Luminal Side of Atherosclerotic Lesions Umbarawan Y, Enoura A, Ogura H, Sato T, Horikawa M, Ishii T, Sunaga H, Matsui H, Yokoyama T, Kawakami R, Maeno T, Setou M, Kurabayashi M, Iso T. Iso T Int Heart J. 62 666-676
61 2021 Pathophysiological and diagnostic importance of fatty acid-binding protein 1 in heart failure with preserved ejection fraction Harada T, Araki T, Sunaga H, Kagami K, Yoshida K, Kato T, Kawakami R, Tomono J, Wada N, Iso T, Kurabayashi M, Obokata M. Sci Rep. 2021 Oct 27;11(1): Obokata M Sci Rep. 11 21175
62 2021 Pulmonary Artery Diameter (PAD) and the Pulmonary Artery to Aorta Ratio (PAD/AAD) as Assessed by Non-contrast Cardiac CT: The Association with Left Ventricular (LV) Remodeling and the LV Function Nguyen-Thu H, Ohyama Y, Taketomi-Takahashi A, Nguyen-Cong T, Sumiyoshi H, Nakamura T, Kurabayashi M, Tsushima Y. Ohyama Y Intern Med   8605-21
63 2021 Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury. Kawakami R, Matsui M, Konno A, Kaneko R, Shrestha S, Shrestha S, Sunaga H, Hanaoka H, Goto S, Hosojima M, Kabasawa H, Obokata M, Koitabashi N, Matsui H, Sasaki T, Saito A, Yanagita M, Hirai H, Kurabayashi M, Iso T. Iso T J Pathol 255 362-373
64 2021 Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice Umbarawan Y, Kawakami R, Syamsunarno MRAA, Obinata H, Yamaguchi A, Hanaoka H, Hishiki T, Hayakawa N, Koitabashi N, Sunaga H, Matsui H, Kurabayashi M, Iso T. Iso T Metabolites 11 881
65 2021 Cardiac Metabolism and Contractile Function in Mice with Reduced Trans-Endothelial Fatty Acid Transport Iso T Kurabayashi M Iso T Metabolites 11 889

 

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