No.	Year	Title	Author	Corresponding	Journal	Vol.	Pages
1	2013	Posttranscriptional Regulation of Histone Lysine Methyltransferase GLP in Embryonic Male Mouse Germ Cells.	Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y	Shinkai Y	Biol Reprod.	88	36
2	2013	Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes.	Takahashi M, Kamei Y, Ehara T, Yuan X, Suganami T, Takai-Igarashi T, Hatada I, Ogawa Y	Ogawa Y	Biochem Biophys Res Commun.	434	873-878
3	2013	miR-29 represses the activities of DNA methyltransferases and DNA demethylases.	Morita S, Horii T, Kimura M, Ochiya T, Tajima S, Hatada I	Hatada, I	Int J Mol Sci	14	14647-14658
4	2013	MiR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells.	Gailhouste L, Gomez-Santos L, Hagiwara K, Hatada I, Kitagawa N, Kawaharada K, Thirion M, Kosaka N, Takahashi RU, Shibata T, Miyajima A, Ochiya T	Ochiya T	Hepatology	58	1153-1165
5	2013	Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System.	Horii T, Tamura D, Morita S, Kimura M, , Hatada I	Hatada, I	Int J Mol Sci	14	19774-19781
6	2013	MiR-184 regulates insulin secretion through repression of Slc25a22.	Morita S, Horii T, Kimura M, , Hatada I	Hatada, I	PeerJ	1	e162
7	2013	Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system.	Horii T, Morita S, Kimura M, Kobayashi R, Tamura D, Takahashi R, Kimura H, Suetake I, Ohata H, Okamoto K, Tajima S, Ochiya T, Abe Y, Hatada I	Hatada, I	PeerJ	1	e230
8	2014	Paternal Allele Influences High Fat Diet-Induced Obesity.	Morita S, Horii T, Kimura M, Arai Y, Kamai Y, Ogawa Y, Hatada I	Hatada, I	PLoS ONE	9	e85477
9	2014	Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering.	Horii T, Arai Y, Yamazai M, Morita S, Kimura M, Itoh M, Abe Y, Hatada I	Hatada, I	Scientific Reports	4	4513
10	2015	Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the FattyAcid β-Oxidation Genes in the Postnatal Liver.	Ehara T, Kamei Y, Yuan X, Takahashi M, Kanai S, Tamura E, Tsujimoto K, Tamiya T, Nakagawa Y, Shimano H, Takai-Igarashi T, Hatada I, Suganami T, Hashimoto K, Ogawa Y.	Ogawa Y	Diabetes	64	775-784
11	2015	p53 Suppresses Tetraploid Development in Mice.	Horii T, Yamamoto M, Morita S, Kimura M, Nagao Y, Hatada I	Hatada, I	Scientific Reports	5	8907
13	2015	Genome Editing Using Mammalian Haploid Cells.	Horii T, Hatada I	Hatada I	Int J Mol Sci	16	23604-23614
14	2015	Global DNA hypomethylation and hypoxia-induced expression of the ten eleven translocation (TET) family, TET1, in scleroderma fibroblasts.	Hattori M, Yokoyama Y, Hattori T1, Motegi S, Amano H, Hatada I, Ishikawa O.	Amano H	Exp Dermatol.	24	841-846
15	2016	Genome editing: A breakthrough in life science and medicine.	Hatada I, Horii T	Hatada I	Endocr J	63	105-110
16	2016	Challenges to increasing targeting efficiency in genome engineering.	Horii T, Hatada I	Horii T	J Reprod Dev	62	7-9
17	2016	5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability.	Kafer GR, Li X, Horii T, Suetake I, Tajima S, Hatada I, Carlton PM	Carlton PM	Cell Rep	14	1283-1292
18	2016	Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity.	Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I.	Hatada I	Sci Rep	6	21693
19	2016	Structure and Engineering of Francisella novicida Cas9.	Hirano H, Gootenberg JS, Horii T3, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F,Nishimasu H, Nureki O	Nureki O	Cell	164	950-961
20	2016	Production of genome-edited pluripotent stem cells and mice by CRISPR/Cas.	Horii T, Hatada I	Hatada I	Endocr J	63	213-219
21	2016	The HUS1B promoter is hypomethylated in the placentas of low-birth-weight infants.	Rumbajan JM, Yamaguchi Y, Nakabayashi K, Higashimoto K, Yastuki H, Nishioka K, Matsuoka K, Aoki S, Toda S, Takeda S, Seki H, Hatada I, Hata K, Soejima H, Joh K.	Soejima H, Joh K	Gene	583	141-146
22	2016	Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells.	Horii T, Hatada I.	Horii T	J Reprod Dev.	62	331-335
23	2016	Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions.	Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.	Hatada I	Nat Biotech.	34	1060-1065
24	2016	Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.	Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F.	Tokunaga F	Nat Commun.	7	12547
25	2017	TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes.	Hasei J, Teramura T, Takehara T, Onodera Y, Horii T, Olmer M, Hatada I, Fukuda K, Ozaki T, Lotz MK, Asahara H.	Asahara H	Sci Rep	7	42990
26	2017	Efficient generation of conditional knockout mice via sequential introduction of lox sites.	Horii T, Morita S, Kimura M, Terawaki N, Shibutani M, Hatada I.	Hatada I.	Sci Rep	7	7891
27	2017	Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions.	Morita S, Horii T, Hatada I.	Hatada I.	Methods Mol Biol.	1767	419-428
28	2018	Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.	Yuan X, Tsujimoto K, Hashimoto K, Kawahori K, Hanzawa N, Hamaguchi M, Seki T, Nawa M, Ehara T, Kitamura Y, Hatada I, Konishi M, Itoh N, Nakagawa Y, Shimano H, Takai-Igarashi T, Kamei Y, Ogawa Y.	Ogawa Y	Nat Commun.	9	636
29	2019	Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9.	Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O.	Nureki O	Nat Commun.	10	1968
30	2020	DNA methylation analysis of multiple imprinted DMRs in Sotos syndrome reveals IGF2-DMR0 as a DNA methylation-dependent, P0 promoter-specific enhancer.	Watanabe H, Higashimoto K, Miyake N, Morita S, Horii T, Kimura M, Suzuki T, Maeda T, Hidaka H, Aoki S, Yatsuki H, Okamoto N, Uemura T, Hatada I, Matsumoto N, Soejima H.	Soejima H	FASEB J.	34	960-973
31	2020	Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.	Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, Georgel P, Hatada I, Chang B, Kerur N, Ambati BK, Ambati J, Gelfand BD.	Gelfand BD	Proc Natl Acad Sci U S A.	117	2579-2587
32	2020	Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform.	Morita S, Horii T, Kimura M, Hatada I.	Hatada I	Int J Mol Sci.	21	E1574
33	2020	Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing.	Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y.	Hashimoto K, Ogawa Y.	Sci Rep	10	5181
34	2020	Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome.	Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M & Hatada I.	Hatada I.	Genome Biology	21	77
35	2020	Calcium-Free and Cytochalasin B Treatment Inhibits Blastomere Fusion in 2-Cell Stage Embryos for the Generation of Floxed Mice via Sequential Electroporation.	Horii T, Kobayashi R, Kimura M, Morita S, Hatada I	Hatada I.	Cells	9	pii: E1088
36	2020	Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity.	Kohro Y, Matsuda T, Yoshihara K, Kohno K, Koga K, Katsuragi R, Oka T, Tashima R, Muneta S, Yamane T, Okada S, Momokino K, Furusho A, Hamase K, Oti T, Sakamoto H, Hayashida K, Kobayashi R, Horii T, Hatada I, Tozaki-Saitoh H, Mikoshiba K, Taylor V, Inoue K, Tsuda M	Tsuda M	Nat Neurosci.	23	1376-1387
37	2021	The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice.	Sugimoto H, Horii T, Hirota J, Sano Y, Shinoda Y, Konno A, Hirai H, Ishizaki Y, Hirase H, Hatada I, Furuichi T & Sadakata T.	Sadakata T.	Molecular Brain	14	52
38	2021	α1A-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice.	Shiraishi Y, Koga K, Yamagata R, Hatada I, Shiratori-Hayashi M, Tsuda M	Tsuda M	Molecular Brain	14	55
39	2021	Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling.	Kawanabe R, Yoshihara K, Hatada I, Tsuda M	Tsuda M	Molecular Brain	14	79
40	2021	Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.	Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K.	Yoshida K.	Commun Biol.	4	1204
41	2022	Stress-induced antinociception to noxious heat requires α 1A-adrenaline receptors of spinal inhibitory neurons in mice	Uchiyama S, Yoshihara K, Kawanabe R, Hatada I, Koga K, Tsuda M.	Tsuda M	Molecular Brain	15	6
42	2022	Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+-activated large-conductance K + channels and motor coordination	Watanave M, Takahashi N, Hosoi N, Konno A, Yamamoto H, Yasui H, Kawachi M, Horii T, Matsuzaki Y, Hatada I, Hirai H.	Hirai H	Proc Natl Acad Sci U S A	119	e2113336119